Latest publications of CIBIO affiliates (last updated on June 1st, 2023)
Zaghi M, Longo F, Massimino L, Rubio A, Bido S, Mazzara PG, Bellini E, Banfi F, Podini P, Maltecca F, Zippo A, Broccoli V, Sessa A (2023) SETD5 haploinsufficiency affects mitochondrial compartment in neural cells. Mol Autism, 14(1):20, doi:10.1186/s13229-023-00550-9.
http://www.ncbi.nlm.nih.gov/pubmed/37264456
Smurova K, Damizia M, Irene C, Stancari S, Berto G, Perticari G, Iacovella MG, D'Ambrosio I, Giubettini M, Philippe R, Baggio C, Callegaro E, Casagranda A, Corsini A, Polese VG, Ricci A, Dassi E, De Wulf P (2023) Rio1 downregulates centromeric RNA levels to promote the timely assembly of structurally fit kinetochores. Nat Commun, 14(1):3172, doi:10.1038/s41467-023-38920-9.
http://www.ncbi.nlm.nih.gov/pubmed/37263996
Barozzi C, Zacchini F, Corradini AG, Morara M, Serra M, De Sanctis V, Bertorelli R, Dassi E, Montanaro L (2023) Alterations of ribosomal RNA pseudouridylation in human breast cancer. NAR Cancer, 5(2):zcad026, doi:10.1093/narcan/zcad026.
http://www.ncbi.nlm.nih.gov/pubmed/37260601
Lago C, Gianesello M, Santomaso L, Leva G, Ballabio C, Anderle M, Antonica F, Tiberi L (2023) Medulloblastoma and high-grade glioma organoids for drug screening, lineage tracing, co-culture and in vivo assay. Nat Protoc, doi:10.1038/s41596-023-00839-2.
http://www.ncbi.nlm.nih.gov/pubmed/37248391
Brentari I, Zadorozhna M, Denti MA, Giorgio E (2023) RNA therapeutics for neurological diseases. Br Med Bull, doi:10.1093/bmb/ldad010.
http://www.ncbi.nlm.nih.gov/pubmed/37210633
Pagnoux C, Berti A (2023) Advances in the pharmacotherapeutic management of eosinophilic granulomatosis with polyangiitis. Expert Opin Pharmacother, doi:10.1080/14656566.2023.2216379.
http://www.ncbi.nlm.nih.gov/pubmed/37204027
Caliari A, Hanczyc MM, Imai M, Xu J, Yomo T (2023) Quantification of Giant Unilamellar Vesicle Fusion Products by High-Throughput Image Analysis. Int J Mol Sci, 24(9), doi:10.3390/ijms24098241.
http://www.ncbi.nlm.nih.gov/pubmed/37175944
Porcari S, Benech N, Valles-Colomer M, Segata N, Gasbarrini A, Cammarota G, Sokol H, Ianiro G (2023) Key determinants of success in fecal microbiota transplantation: From microbiome to clinic. Cell Host Microbe, 31(5):712-733, doi:10.1016/j.chom.2023.03.020.
http://www.ncbi.nlm.nih.gov/pubmed/37167953
Emmi G, Bettiol A, Gelain E, Bajema IM, Berti A, Burns S, Cid MC, Cohen Tervaert JW, Cottin V, Durante E, Holle JU, Mahr AD, Del Pero MM, Marvisi C, Mills J, Moiseev S, Moosig F, Mukhtyar C, Neumann T, Olivotto I, Salvarani C, Seeliger B, Sinico RA, Taillé C, Terrier B, Venhoff N, Bertsias G, Guillevin L, Jayne DRW, Vaglio A (2023) Evidence-Based Guideline for the diagnosis and management of eosinophilic granulomatosis with polyangiitis. Nat Rev Rheumatol, 19(6):378-393, doi:10.1038/s41584-023-00958-w.
http://www.ncbi.nlm.nih.gov/pubmed/37161084
Carreira ASA, Ravera S, Zucal C, Thongon N, Irene C, Astigiano C, Bertola N, Buongiorno A, Roccuzzo M, Bisio A, Pardini B, Nencioni A, Bruzzone S, Provenzani A (2023) Mitochondrial rewiring drives metabolic adaptation to NAD(H) shortage in triple negative breast cancer cells. Neoplasia, 41:100903, doi:10.1016/j.neo.2023.100903.
http://www.ncbi.nlm.nih.gov/pubmed/37148658
Manghi P, Blanco-Míguez A, Manara S, NabiNejad A, Cumbo F, Beghini F, Armanini F, Golzato D, Huang KD, Thomas AM, Piccinno G, Punčochář M, Zolfo M, Lesker TR, Bredon M, Planchais J, Glodt J, Valles-Colomer M, Koren O, Pasolli E, Asnicar F, Strowig T, Sokol H, Segata N (2023) MetaPhlAn 4 profiling of unknown species-level genome bins improves the characterization of diet-associated microbiome changes in mice. Cell Rep, 42(5):112464, doi:10.1016/j.celrep.2023.112464.
http://www.ncbi.nlm.nih.gov/pubmed/37141097
Manara S, Selma-Royo M, Huang KD, Asnicar F, Armanini F, Blanco-Miguez A, Cumbo F, Golzato D, Manghi P, Pinto F, Valles-Colomer M, Amoroso L, Corrias MV, Ponzoni M, Raffaetà R, Cabrera-Rubio R, Olcina M, Pasolli E, Collado MC, Segata N (2023) Maternal and food microbial sources shape the infant microbiome of a rural Ethiopian population. Curr Biol, 33(10):1939-1950.e4, doi:10.1016/j.cub.2023.04.011.
http://www.ncbi.nlm.nih.gov/pubmed/37116481
Maines E, Moretti M, Vitturi N, Gugelmo G, Fasan I, Lenzini L, Piccoli G, Gragnaniello V, Maiorana A, Soffiati M, Burlina A, Franceschi R (2023) Understanding the Pathogenesis of Cardiac Complications in Patients with Propionic Acidemia and Exploring Therapeutic Alternatives for Those Who Are Not Eligible or Are Waiting for Liver Transplantation. Metabolites, 13(4), doi:10.3390/metabo13040563.
http://www.ncbi.nlm.nih.gov/pubmed/37110221
O'Toole PW, Ghosh TS, Goswami S, Manghi P, Segata N, Shanahan F (2023) Translating the Microbiome: What's the Target? Gastroenterology, doi:10.1053/j.gastro.2023.04.008.
http://www.ncbi.nlm.nih.gov/pubmed/37094661
Prodi E, Comacchio C, Gilardoni E, Di Nitto C, Puca E, Neri D, De Luca R (2023) An Antibody Targeting Fibroblast Activation Protein Simultaneously Fused to Interleukin-2 and Tumor Necrosis Factor Selectively Localizes to Neoplastic Lesions. Antibodies (Basel), 12(2), doi:10.3390/antib12020029.
http://www.ncbi.nlm.nih.gov/pubmed/37092450
Briata P, Mastracci L, Zapparoli E, Caputo L, Ferracci E, Silvestri A, Garuti A, Hamadou MH, Inga A, Marcaccini E, Grillo F, Bucci G, Puri PL, Beznoussenko G, Mironov A, Chiacchiera F, Gherzi R (2023) LncRNA EPR regulates intestinal mucus production and protects against inflammation and tumorigenesis. Nucleic Acids Res, doi:10.1093/nar/gkad257.
http://www.ncbi.nlm.nih.gov/pubmed/37070602
Savoca V, Rivosecchi J, Gaiatto A, Rossi A, Mosca R, Gialdini I, Zubovic L, Tebaldi T, Macchi P, Cusanelli E (2023) TERRA stability is regulated by RALY and polyadenylation in a telomere-specific manner. Cell Rep, 42(4):112406, doi:10.1016/j.celrep.2023.112406.
http://www.ncbi.nlm.nih.gov/pubmed/37060569
Meškytė EM, Pezzè L, Bartolomei L, Forcato M, Bocci IA, Bertalot G, Barbareschi M, Oliveira-Ferrer L, Bisio A, Bicciato S, Baltriukienė D, Ciribilli Y (2023) ETV7 reduces inflammatory responses in breast cancer cells by repressing the TNFR1/NF-κB axis. Cell Death Dis, 14(4):263, doi:10.1038/s41419-023-05718-y.
http://www.ncbi.nlm.nih.gov/pubmed/37041130
Zanovello L, Löffler RJG, Caraglio M, Franosch T, Hanczyc MM, Faccioli P (2023) Survival strategies of artificial active agents. Sci Rep, 13(1):5616, doi:10.1038/s41598-023-32267-3.
http://www.ncbi.nlm.nih.gov/pubmed/37024516
Louca P, Meijnikman AS, Nogal A, Asnicar F, Attaye I, Vijay A, Kouraki A, Visconti A, Wong K, Berry SE, Leeming ER, Mompeo O, Tettamanzi F, Baleanu AF, Falchi M, Hadjigeorgiou G, Wolf J, Acherman YIZ, Van de Laar AW, Gerdes VEA, Michelotti GA, Franks PW, Segata N, Mangino M, Spector TD, Bulsiewicz WJ, Nieuwdorp M, Valdes AM, Menni C (2023) The secondary bile acid isoursodeoxycholate correlates with post-prandial lipemia, inflammation, and appetite and changes post-bariatric surgery. Cell Rep Med, 4(4):100993, doi:10.1016/j.xcrm.2023.100993.
http://www.ncbi.nlm.nih.gov/pubmed/37023745
Perini S, Filosi M, Italian Autism Network, Domenici E (2023) Candidate biomarkers from the integration of methylation and gene expression in discordant autistic sibling pairs. Transl Psychiatry, 13(1):109, doi:10.1038/s41398-023-02407-4.
http://www.ncbi.nlm.nih.gov/pubmed/37012247
Battistella I, Cutarelli A, Zasso J, Clerici M, Sala C, Marcatili M, Conti L (2023) Cortical Astrocyte Progenitors and Astrocytes from Human Pluripotent Stem Cells. J Pers Med, 13(3), doi:10.3390/jpm13030538.
http://www.ncbi.nlm.nih.gov/pubmed/36983719
Pezzotta A, Brioschi L, Carbone S, Mazzoleni B, Bontempi V, Monastra F, Mauri L, Marozzi A, Mione M, Pistocchi A, Viani P (2023) Combined Inhibition of Hedgehog and HDAC6: In Vitro and In Vivo Studies Reveal a New Role for Lysosomal Stress in Reducing Glioblastoma Cell Viability. Int J Mol Sci, 24(6), doi:10.3390/ijms24065771.
http://www.ncbi.nlm.nih.gov/pubmed/36982845
Vigna J, Sighel D, Rosatti EF, Defant A, Pancher M, Sidarovich V, Quattrone A, Mancini I (2023) Expanding the Chemical Space of Arsenicin A-C Related Polyarsenicals and Evaluation of Some Analogs as Inhibitors of Glioblastoma Stem Cell Growth. Mar Drugs, 21(3), doi:10.3390/md21030186.
http://www.ncbi.nlm.nih.gov/pubmed/36976235
Obergasteiger J, Castonguay AM, Pizzi S, Magnabosco S, Frapporti G, Lobbestael E, Baekelandt V, Hicks AA, Pramstaller PP, Gravel C, Corti C, Lévesque M, Volta M (2023) The small GTPase Rit2 modulates LRRK2 kinase activity, is required for lysosomal function and protects against alpha-synuclein neuropathology. NPJ Parkinsons Dis, 9(1):44, doi:10.1038/s41531-023-00484-2.
http://www.ncbi.nlm.nih.gov/pubmed/36973269
Pedrinolla A, Berg OK, Tøien T, Wang E (2023) Aging increases metabolic capacity and reduces work efficiency during handgrip exercise in males. J Appl Physiol (1985), 134(5):1154-1164, doi:10.1152/japplphysiol.00411.2022.
http://www.ncbi.nlm.nih.gov/pubmed/36958347
Hellmich B, Sanchez-Alamo B, Schirmer JH, Berti A, Blockmans D, Cid MC, Holle JU, Hollinger N, Karadag O, Kronbichler A, Little MA, Luqmani RA, Mahr A, Merkel PA, Mohammad AJ, Monti S, Mukhtyar CB, Musial J, Price-Kuehne F, Segelmark M, Teng YKO, Terrier B, Tomasson G, Vaglio A, Vassilopoulos D, Verhoeven P, Jayne D (2023) EULAR recommendations for the management of ANCA-associated vasculitis: 2022 update. Ann Rheum Dis, doi:10.1136/ard-2022-223764.
http://www.ncbi.nlm.nih.gov/pubmed/36927642
Pavani M, Chiroli E, Cancrini C, Gross F, Bonaiuti P, Villa S, Giavazzi F, Matafora V, Bachi A, Fava LL, Lischetti T, Ciliberto A (2023) Triap1 upregulation promotes escape from mitotic-slippage-induced G1 arrest. Cell Rep, 42(3):112215, doi:10.1016/j.celrep.2023.112215.
http://www.ncbi.nlm.nih.gov/pubmed/36917609
Bonomo I, Assoni G, La Pietra V, Canarutto G, Facen E, Donati G, Zucal C, Genovese S, Micaelli M, Pérez-Ràfols A, Robbiati S, Kontoyannis DL, De Matteo M, Fragai M, Seneci P, Marinelli L, Arosio D, Piazza S, Provenzani A (2023) HuR modulation counteracts lipopolysaccharide response in murine macrophages. Dis Model Mech, 16(3), doi:10.1242/dmm.050120.
http://www.ncbi.nlm.nih.gov/pubmed/36912171
Pedrazzoli E, Bianchi A, Umbach A, Amistadi S, Brusson M, Frati G, Ciciani M, Badowska KA, Arosio D, Miccio A, Cereseto A, Casini A (2023) An optimized SpCas9 high-fidelity variant for direct protein delivery. Mol Ther, doi:10.1016/j.ymthe.2023.03.007.
http://www.ncbi.nlm.nih.gov/pubmed/36905119
Blanco-Míguez A, Beghini F, Cumbo F, McIver LJ, Thompson KN, Zolfo M, Manghi P, Dubois L, Huang KD, Thomas AM, Nickols WA, Piccinno G, Piperni E, Punčochář M, Valles-Colomer M, Tett A, Giordano F, Davies R, Wolf J, Berry SE, Spector TD, Franzosa EA, Pasolli E, Asnicar F, Huttenhower C, Segata N (2023) Extending and improving metagenomic taxonomic profiling with uncharacterized species using MetaPhlAn 4. Nat Biotechnol, doi:10.1038/s41587-023-01688-w.
http://www.ncbi.nlm.nih.gov/pubmed/36823356
Visconti A, Rossi N, Deriš H, Lee KA, Hanić M, Trbojević-Akmačić I, Thomas AM, Bolte LA, Björk JR, Hooiveld-Noeken JS, Board R, Harland M, Newton-Bishop J, Harries M, Sacco JJ, Lorigan P, Shaw HM, de Vries EGE, Fehrmann RSN, Weersma RK, Spector TD, Nathan P, Hospers GAP, Sasieni P, Bataille V, Lauc G, Falchi M (2023) Total serum N-glycans associate with response to immune checkpoint inhibition therapy and survival in patients with advanced melanoma. BMC Cancer, 23(1):166, doi:10.1186/s12885-023-10511-3.
http://www.ncbi.nlm.nih.gov/pubmed/36805683
Cottini M, Lombardi C, Comberiati P, Landi M, Berti A, Ventura L (2023) Small airway dysfunction in asthmatic patients treated with as-needed SABA monotherapy: A perfect storm. Respir Med, 209:107154, doi:10.1016/j.rmed.2023.107154.
http://www.ncbi.nlm.nih.gov/pubmed/36796546
Biasini E, Faccioli P (2023) Functional, pathogenic, and pharmacological roles of protein folding intermediates. Proteins, doi:10.1002/prot.26479.
http://www.ncbi.nlm.nih.gov/pubmed/36779817
Marchioretti C, Zanetti G, Pirazzini M, Gherardi G, Nogara L, Andreotti R, Martini P, Marcucci L, Canato M, Nath SR, Zuccaro E, Chivet M, Mammucari C, Pacifici M, Raffaello A, Rizzuto R, Mattarei A, Desbats MA, Salviati L, Megighian A, Sorarù G, Pegoraro E, Belluzzi E, Pozzuoli A, Biz C, Ruggieri P, Romualdi C, Lieberman AP, Babu GJ, Sandri M, Blaauw B, Basso M, Pennuto M (2023) Defective excitation-contraction coupling and mitochondrial respiration precede mitochondrial Ca Nat Commun, 14(1):602, doi:10.1038/s41467-023-36185-w.
http://www.ncbi.nlm.nih.gov/pubmed/36746942
Cucchi A, Bettini S, Ghensi P, Fiorino A, Corinaldesi G (2023) Vertical ridge augmentation with Ti-reinforced dense polytetrafluoroethylene (d-PTFE) membranes or Ti-meshes and collagen membranes: 3-year results of a randomized clinical trial. Clin Implant Dent Relat Res, 25(2):352-369, doi:10.1111/cid.13173.
http://www.ncbi.nlm.nih.gov/pubmed/36646986
Scalisi S, Pisignano D, Cella Zanacchi F (2023) Single-molecule localization microscopy goes quantitative. Microsc Res Tech, 86(4):494-504, doi:10.1002/jemt.24281.
http://www.ncbi.nlm.nih.gov/pubmed/36601697
Ravelli F, Masè M, Cristoforetti A, Avogaro L, D'Amato E, Tessarolo F, Piccoli F, Graffigna A (2023) Quantitative assessment of transmural fibrosis profile in the human atrium: evidence for a three-dimensional arrhythmic substrate by slice-to-slice histology. Europace, 25(2):739-747, doi:10.1093/europace/euac187.
http://www.ncbi.nlm.nih.gov/pubmed/36349600
Boleto G, Berti A, Merkel PA, Aydin SZ, Direskeneli H, Dejaco C, Hassett LC, Carmona L, Ramiro SOMERACT Vasculitis Working Group, (2023) Measurement Properties of Outcome Instruments for Large-Vessel Vasculitis: A Systematic Literature Review. J Rheumatol, 50(6):789-798, doi:10.3899/jrheum.220149.
http://www.ncbi.nlm.nih.gov/pubmed/36319004
Chevet B, Cornec D, Casal Moura M, Cornec-Le Gall E, Fervenza FC, Warrington KJ, Specks U, Berti A (2023) Diagnosing and treating ANCA-associated vasculitis: an updated review for clinical practice. Rheumatology (Oxford), 62(5):1787-1803, doi:10.1093/rheumatology/keac623.
http://www.ncbi.nlm.nih.gov/pubmed/36315063
Berti A, Hillion S, Konig MF, Moura MC, Hummel AM, Carmona E, Peikert T, Fervenza FC, Kallenberg CGM, Langford CA, Merkel PA, Monach PA, Seo P, Spiera RF, Brunetta P, St Clair EW, Harris KM, Stone JH, Grandi G, Pers JO, Specks U, Cornec D (2023) Autoreactive Plasmablasts After B Cell Depletion With Rituximab and Relapses in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. Arthritis Rheumatol, 75(5):736-747, doi:10.1002/art.42388.
http://www.ncbi.nlm.nih.gov/pubmed/36281741