Latest publications of CIBIO affiliates (last updated on February 1st, 2026)
Carreira ÁSA, Ciuffreda M, Thongon N, Haughey CM, Pickard A, Eddie SL, Steele RE, Cerri E, Belli R, Peroni D, Facen E, Caffa I, Ghanem M, Nencioni A, Lunardi A, Tebaldi T, Mills IG, Provenzani A (2026) Nicotinamide N-Methyl Transferase (NNMT) Sustains Innate Sensitivity to NAMPT Inhibition in YAP-dependent Stem-like/Mesenchymal Prostate Cancer. Int J Biol Sci, 22(3):1126-1141, doi:10.7150/ijbs.120532.
http://www.ncbi.nlm.nih.gov/pubmed/41608637
Serafini MM, Midali M, Grumelli G, Cutarelli A, Marinovich M, Conti L, Viviani B (2026) Transcript-protein discrepancy of glutamatergic receptor subunits in human iPSC-derived neurons: Implications for neurotoxicity testing. Toxicol Lett, 417:111834, doi:10.1016/j.toxlet.2026.111834.
http://www.ncbi.nlm.nih.gov/pubmed/41592671
Zaccaria C, Malkoç A, Auslender I, Heydari Y, Canossa M, Vignoli B, Pavesi L (2026) Investigation of synaptic connectivity in functional in vitro neuronal assemblies. Cell Rep Methods, 6(1):101265, doi:10.1016/j.crmeth.2025.101265.
http://www.ncbi.nlm.nih.gov/pubmed/41592533
Marini M, Iseppi M, Quintarelli S, Tedoldi F, Ravelli F, Bonmassari R, Arbustini E (2026) Autosomal Recessive Atrial Dilated Cardiomyopathy Due to J Cardiovasc Dev Dis, 13(1), doi:10.3390/jcdd13010037.
http://www.ncbi.nlm.nih.gov/pubmed/41590864
Ferrero G, Mastrocola R, Tarallo S, Pardini B, Scheijen J, van de Waarenburg M, Gallo G, Chatziioannou AC, Robinot N, Keski-Rahkonen P, Piccinno G, Segata N, Aglago EK, Hughes DJ, Jenab M, Schalkwijk CG, Naccarati A (2026) Integrative analyses of dicarbonyls and advanced glycation end-products with multiomic profiles across tissue, plasma and stool samples reveal methylglyoxal accumulation in colon cancer. Free Radic Biol Med, 246:518-530, doi:10.1016/j.freeradbiomed.2026.01.034.
http://www.ncbi.nlm.nih.gov/pubmed/41579975
Vutera Cuda A, Bajaj S, Manara V, Bellosta P (2026) Noc1 downregulation induces nucleolar stress and upregulates p53 isoforms, with a robust increase of the truncated p53E isoform in Drosophila wing discs. G3 (Bethesda), doi:10.1093/g3journal/jkaf313.
http://www.ncbi.nlm.nih.gov/pubmed/41533679
Espeit L, Besson T, Sabater-Pastor F, Tondut J, Hoogkamer W, Kram R, Lemire M, Millet GP, Savoldelli A, Vercruyssen F, Vernillo G, Millet GY (2026) Correlations Between the Metabolic Costs of Level and Graded Running: A Secondary Analysis of the Literature. Sports Med, doi:10.1007/s40279-025-02381-5.
http://www.ncbi.nlm.nih.gov/pubmed/41493537
Donato L, Zerti D, Babiloni-Chust I, Passacantando M, Flati V, Feligioni M, Carl M, Rinaldi C, Poggi L, D'Angelo R, Maccarone R (2026) Comprehensive transcriptomic analysis reveals canonical and novel pathways modulated by nanoceria in mammalian retinal degeneration. Sci Rep, 16(1):3689, doi:10.1038/s41598-025-33260-8.
http://www.ncbi.nlm.nih.gov/pubmed/41484209
Manghi P, Antonello G, Schiffer L, Golzato D, Wokaty A, Beghini F, Mirzayi C, Long K, Gravel-Pucillo K, Piccinno G, Gamboa-Tuz SD, Bonetti A, D'Amato G, Azhar R, Eckenrode K, Zohra F, Giunchiglia V, Keller M, Pedrotti A, Likhotkin I, Elsafoury S, Geistlinger L, Blanco-Miguez A, Thomas AM, Zolfo M, Ramos M, Valles-Colomer M, Tamburini S, Asnicar F, Jones HE, Huttenhower C, Carey V, Davis S, Pasolli E, Oh S, Segata N, Waldron L (2025) Meta-analysis of 22,710 human microbiome metagenomes defines an oral-to-gut microbial enrichment score and associations with host health and disease. Nat Commun, 17(1):196, doi:10.1038/s41467-025-66888-1.
http://www.ncbi.nlm.nih.gov/pubmed/41436448
Giaquinta R, Andric A, Scheppach M, Weiss AKH (2026) Synergistic Roles of FAHD-1 and PYC-1 in Mitochondrial Function, Behavior, and Longevity in C. elegans. Adv Biol (Weinh), 10(1):e00410, doi:10.1002/adbi.202500410.
http://www.ncbi.nlm.nih.gov/pubmed/41424331
Biba DA, Makarova KS, Wolf YI, Waldron L, Koonin EV, Rochman ND (2025) Ecological determinants of altruism in prokaryote antivirus defense. Biol Direct, 21(1):7, doi:10.1186/s13062-025-00699-8.
http://www.ncbi.nlm.nih.gov/pubmed/41422249
Sarhan MS, Abdalrahem A, Maixner F, Fuchsberger C (2025) De novo assembly of complete circular mitochondrial genomes from 2,695 fungal species. Sci Data, 13(1):28, doi:10.1038/s41597-025-06447-x.
http://www.ncbi.nlm.nih.gov/pubmed/41413074
Anfuso B, Velnati S, Selvestrel D, Garlant C, Ferracci E, Baj G, Parisse P, Overi D, Bertolio R, Bulla R, Sonzogni A, Bramuzzo M, Casalis L, Cocomello N, Baratta F, Del Ben M, Giraudi P, Tiribelli C, Rosso N, Mastronardi M, Tarchi P, Pinamonti M, Zanconati F, de Manzini N, Gaudio E, Palmisano S, Bonazza D, Del Sal G, Carpino G, Chiacchiera F, Sorrentino G (2025) An organotypic model of ductular reaction reveals a mevalonate-dependent vulnerability in reactive biliary cells. Cell Rep, 44(12):116681, doi:10.1016/j.celrep.2025.116681.
http://www.ncbi.nlm.nih.gov/pubmed/41389211
Witteveldt J, Liu Z, Ariza-Cosano A, Ramirez C, Walters JL, Marchante PG, Maas L, Friman ET, Ivens A, Tebaldi T, Heras SR, Marks H, Macias S (2025) Double stranded RNA sensing is silenced during early embryonic development. Nat Commun, 16(1):11438, doi:10.1038/s41467-025-66352-0.
http://www.ncbi.nlm.nih.gov/pubmed/41381491
Asnicar F, Manghi P, Fackelmann G, Baldanzi G, Bakker E, Ricci L, Piccinno G, Piperni E, Mladenovic K, Amati F, Arrè A, Ganesh S, Giordano F, Davies R, Wolf J, Bermingham KM, Berry SE, Spector TD, Segata N (2025) Gut micro-organisms associated with health, nutrition and dietary interventions. Nature, doi:10.1038/s41586-025-09854-7.
http://www.ncbi.nlm.nih.gov/pubmed/41372407
Bartolomei L, Ciribilli Y, Brugnara S, Reggiani F, Moretta GM, Petito M, Marcaccini E, Ambrosio M, Mosci C, Pfeffer U, Amaro A, Monti P, Bisio A (2025) Exploring p53 isoforms: unraveling heterogeneous p53 tumor suppressor functionality in uveal melanoma. Cell Death Discov, 12(1):39, doi:10.1038/s41420-025-02891-1.
http://www.ncbi.nlm.nih.gov/pubmed/41350348
Pope R, Visconti A, Zhang X, Louca P, Baleanu AF, Lin Y, Asnicar F, Bermingham K, Wong KE, Michelotti GA, Wolf J, Segata N, Berry SE, Spector TD, Leeming ER, Gibson R, Menni C, Falchi M (2025) Faecal metabolites as a readout of habitual diet capture dietary interactions with the gut microbiome. Nat Commun, 16(1):10051, doi:10.1038/s41467-025-66046-7.
http://www.ncbi.nlm.nih.gov/pubmed/41345102
Hazekawa M, Ishibashi D, Altieri A, Spiridonov EA, Dmitriev NA, Lukyanenko ER, Biasini E, Kurkin AV (2025) Novel anti-prion compounds screening in prion-infected cell culture model combined with surface plasmon resonance analysis. Sci Rep, 15(1):45423, doi:10.1038/s41598-025-29865-8.
http://www.ncbi.nlm.nih.gov/pubmed/41298786
Carrier A, Manghi P, Silva CAC, Lahmar I, Suissa D, Iebba V, Almonte AA, Ajami NJ, Birebent R, Laheurte C, Schreibelt G, Lemant L, Fahrner JE, de Sousa E, Berthier F, Villemonteix J, Chevalier MF, Piccinno G, Hocquet D, Lebhar I, Maeurer M, Caillat-Zucman S, Kobold S, Kroemer G, Derosa L, Launay O, Pieper DH, Vital M, Santos-Peral A, Zaucha M, García-Bengoa M, Thorn-Seshold J, Stirling H, Golden E, Bol KF, White MG, Sahasrabhojane PV, Hoballah YM, Losh JS, DePinho CR, Dondossola E, de Vries IJM, Adotevi O, Wargo JA, Rothenfußer S, Segata N, Formenti S, Zitvogel L (2025) Gut microbiota: a new factor modulating the immunizing potential of viral and cancer vaccines. Res Sq, doi:10.21203/rs.3.rs-4294379/v1.
http://www.ncbi.nlm.nih.gov/pubmed/41282134
Mazza F, Gastaldello F, Dalfovo D, Lattanzi G, Romanel A (2026) HapScoreDB: a database of protein language model functional scores for haplotype-resolved protein sequences. Nucleic Acids Res, 54(D1):D1087-D1097, doi:10.1093/nar/gkaf1184.
http://www.ncbi.nlm.nih.gov/pubmed/41261743
Groza P, Kumari K, Esteva-Socias M, Schott J, Bhattarai DP, Sajkowska JJ, Dasgupta R, Peula C, Destefanis E, Williams C, Marchand V, Wikström P, Wiberg R, Campos AB, Gilthorpe JD, Pop B, Mateus A, Motorin Y, Dassi E, Petzold K, Tuorto F, Aguilo F (2026) Fibrillarin-dependent 2'-O-methylation modulates RPS28 ribosome incorporation and oncogenic translation. Cancer Lett, 639:218124, doi:10.1016/j.canlet.2025.218124.
http://www.ncbi.nlm.nih.gov/pubmed/41260515
Levé M, Manghi P, Bredon M, Lefevre A, Manara S, Armanini F, Emond P, Planchais J, Rolhion N, Segata N, Sokol H (2025) Metabolomics and metagenomics in mice reveal the role of the gut microbiota in tryptophan metabolism. iScience, 28(11):113751, doi:10.1016/j.isci.2025.113751.
http://www.ncbi.nlm.nih.gov/pubmed/41234773
Basso M, Marchioretti C, Zito S, Zuccaro E, Pennuto M (2025) Androgen receptor and its coregulators in sex-biased diseases. Trends Mol Med, doi:10.1016/j.molmed.2025.10.005.
http://www.ncbi.nlm.nih.gov/pubmed/41233252
Galvan A, Guidorizzi E, Carton F, Malatesta M, Calderan L (2025) In Vitro and Ex Vivo Models to Study Molecular Trafficking Across the Human Intestinal Barrier. Int J Mol Sci, 26(21), doi:10.3390/ijms262110535.
http://www.ncbi.nlm.nih.gov/pubmed/41226569
Zubović A, Zamolo G, Kovač L, Raguž M, Zubović L, Belušić M (2025) Differential expression of PD-L1, PD-L2 and inflammasome related proteins (NLRP3, ASC, and Caspase-1) in oral squamous cell carcinoma, lymph node metastases, and benign lesions. J Craniomaxillofac Surg, 53(12):2190-2198, doi:10.1016/j.jcms.2025.10.002.
http://www.ncbi.nlm.nih.gov/pubmed/41224569
Redl S, Zweydorf FV, Gloeckner CJ, Posadas I, Ceña V, Hess MW, Piccoli G, Pérez-Carrión MD (2025) The E193K LRRK2 mutation interferes with the autophagosome processing through the impairment of the LRRK2-Dynein-1 complex. Sci Rep, 15(1):39117, doi:10.1038/s41598-025-26716-4.
http://www.ncbi.nlm.nih.gov/pubmed/41203815
Vavassori L, Rheault F, Nocerino E, Annicchiarico L, Corsini F, Zigiotto L, De Benedictis A, Barbareschi M, Rozzanigo U, Avesani P, Sarubbo S, Petit L (2025) Brain dissection photogrammetry: a tool for studying human white matter connections integrating ex vivo and in vivo multimodal datasets. Nat Commun, 16(1):9801, doi:10.1038/s41467-025-64788-y.
http://www.ncbi.nlm.nih.gov/pubmed/41198692
Tomasi M, Croia L, Zanella I, Gagliardi A, Boscato Sopetto G, Benedet M, Di Lascio G, Gambini G, Berti A, Corbellari R, Grandi G, Grandi A (2025) Investigation on antigen-specific T-cell responses induced by outer membrane vesicles from Front Immunol, 16:1633961, doi:10.3389/fimmu.2025.1633961.
http://www.ncbi.nlm.nih.gov/pubmed/41164183
Lorenzin G, Carlin M (2025) Comparative Meta-Analysis of Long-Read and Short-Read Sequencing for Metagenomic Profiling of the Lower Respiratory Tract Infections. Microorganisms, 13(10), doi:10.3390/microorganisms13102366.
http://www.ncbi.nlm.nih.gov/pubmed/41156825
Falcó I, Allende A, Cutrupi F, Aznar R, Sánchez G, Truchado P (2025) Comparative Analysis of Concentration and Quantification Methods for Antibiotic Resistance Genes and Their Phage-Mediated Dissemination in Treated Wastewater and Biosolids. Pathogens, 14(10), doi:10.3390/pathogens14101050.
http://www.ncbi.nlm.nih.gov/pubmed/41156661
Lorenzin G, Carlin M, Scarparo C, Cardellini M, Tota F, Naselli A (2025) Staphylococcal Scalded Skin Syndrome (SSSS) in a Preterm Infant: Clinical Presentation and Role of Next-Generation Sequencing in Toxin Gene Identification-A Case Report. Antibiotics (Basel), 14(10), doi:10.3390/antibiotics14101017.
http://www.ncbi.nlm.nih.gov/pubmed/41148709
Columbro SF, Tortarolo M, Re Cecconi AD, Piccirillo R, Bendotti C, Biasini E, Pasetto L, Bonetto V (2026) Beneficial effects of synthetic torpor in a fast-progressing mouse model of amyotrophic lateral sclerosis. Exp Neurol, 396:115521, doi:10.1016/j.expneurol.2025.115521.
http://www.ncbi.nlm.nih.gov/pubmed/41135686
Ohlsson C, Li L, Horkeby K, Lawenius L, Colldén H, Sjögren K, Baldanzi G, Engström G, Ärnlöv J, Orho-Melander M, Fall T, Grahnemo L (2025) The circulating dihydrotestosterone/testosterone ratio is increased by gut microbial 5α-reductase activity in females. EBioMedicine, 121:105978, doi:10.1016/j.ebiom.2025.105978.
http://www.ncbi.nlm.nih.gov/pubmed/41124778
Martínez-Balsalobre E, Anchelin M, Hernández-Silva D, Mione MC, Mulero V, Alcaraz-Pérez F, García-Castillo J, Cayuela ML (2025) Telomerase and alternative lengthening of telomeres coexist in the regenerating zebrafish caudal fins. EMBO Rep, 26(23):5776-5798, doi:10.1038/s44319-025-00602-6.
http://www.ncbi.nlm.nih.gov/pubmed/41120592
Trentini G, Cazzanelli G, Lolli G (2025) Protein glycosylation and synaptic transmission: brain glycogen keeps them separated. Brain, doi:10.1093/brain/awaf396.
http://www.ncbi.nlm.nih.gov/pubmed/41108069
Losi G, Vignoli B, Granata R, Lia A, Zonta M, Sansevero G, Pischedda F, Chiavegato A, Santi S, Zentilin L, Berardi N, Ratto GM, Carmignoto G, Canossa M (2025) Spontaneous activity of astrocytes is a stochastic functional signal for memory consolidation. Proc Natl Acad Sci U S A, 122(42):e2500511122, doi:10.1073/pnas.2500511122.
http://www.ncbi.nlm.nih.gov/pubmed/41086220
Sartori S, Babiloni Chust I, Varinelli M, Mattè A, Trionfini P, Tomasoni S, Poggi L (2025) Zebrafish model reveals developmental and hematopoietic functions of ADAMTS13. Biol Open, 14(10), doi:10.1242/bio.062265.
http://www.ncbi.nlm.nih.gov/pubmed/41051174
Gasparotto D, Zanon A, Bonaldo V, Marchiori E, Casagranda M, Di Domenico E, Copat L, Asquini TF, Rigoli M, Feltrin SV, Lopez Lorenzo N, Lolli G, Pennuto M, Requena JR, Rota Stabelli O, Minervini G, Micheletti C, Spagnolli G, Faccioli P, Biasini E (2025) Mapping cryptic phosphorylation sites in the human proteome. EMBO J, 44(22):6704-6731, doi:10.1038/s44318-025-00567-1.
http://www.ncbi.nlm.nih.gov/pubmed/41044218
Martelossi J, Vujovic J, Huang Y, Tatti A, Xu K, Puliga F, Chen Y, Rota Stabelli O, Ghiselli F, Zhang X, Zambonelli A (2025) High-quality assembly of the Chinese white truffle genome and recalibrated divergence time estimate provide insight into the evolutionary dynamics of Tuberaceae. Genome Res, 35(11):2601-2616, doi:10.1101/gr.280368.124.
http://www.ncbi.nlm.nih.gov/pubmed/40841172
Sips F, Virgolin M, Pasculli G, Reali F, Paris A, Janus A, Godfrin Y, Röshammar D, Marchetti L, Knöchel J (2025) Transforming Pediatric Rare Disease Drug Development: Enhancing Clinical Trials and Regulatory Evidence With Virtual Patients. CPT Pharmacometrics Syst Pharmacol, 14(11):1739-1742, doi:10.1002/psp4.70096.
http://www.ncbi.nlm.nih.gov/pubmed/40757668
Menzella F, Chan R, Lombardi C, Berti A, Cottini M (2025) An update on oscillometry in asthma. Expert Rev Respir Med, 19(11):1097-1109, doi:10.1080/17476348.2025.2526774.
http://www.ncbi.nlm.nih.gov/pubmed/40576552
Zigiotto L, Venturini R, Coletta L, Venturini M, Monte DD, Vavassori L, Corsini F, Annicchiarico L, Avesani P, Papagno C, Sarubbo S (2026) Maximizing Tumor Resection and Managing Cognitive Attentional Outcomes: Measures of Impact of Awake Surgery in Glioma Treatment. Neurosurgery, 98(2):365-375, doi:10.1227/neu.0000000000003591.
http://www.ncbi.nlm.nih.gov/pubmed/40539789
Ramirez C, Perenthaler E, Lauria F, Tebaldi T, Viero G (2025) Computational limitations and future needs to unravel the full potential of 2'-O-methylation and C/D box snoRNAs. RNA Biol, 22(1):1-11, doi:10.1080/15476286.2025.2506712.
http://www.ncbi.nlm.nih.gov/pubmed/40377202
Samarra A, Renwick S, Arzamasov AA, Rodionov DA, Spann K, Cabrera-Rubio R, Acuna-Gonzalez A, Martínez-Costa C, Hall L, Segata N, Osterman AL, Bode L, Collado M (2025) Human milk oligosaccharide metabolism and antibiotic resistance in early gut colonizers: insights from bifidobacteria and lactobacilli in the maternal-infant microbiome. Gut Microbes, 17(1):2501192, doi:10.1080/19490976.2025.2501192.
http://www.ncbi.nlm.nih.gov/pubmed/40340669
Romeo S, Vidal-Puig A, Husain M, Ahima R, Arca M, Bhatt DL, Diehl AM, Fontana L, Foo R, Frühbeck G, Kozlitina J, Lonn E, Pattou F, Plat J, Quaggin SE, Ridker PM, Rydén M, Segata N, Tuttle KR, Verma S, Roeters van Lennep J, Benn M, Binder CJ, Jamialahmadi O, Perkins R, Catapano AL, Tokgözoğlu L, Ray KKEuropean Atherosclerosis Society Consensus
, (2025) Clinical staging to guide management of metabolic disorders and their sequelae: a European Atherosclerosis Society consensus statement. Eur Heart J, 46(38):3685-3713, doi:10.1093/eurheartj/ehaf314.
http://www.ncbi.nlm.nih.gov/pubmed/40331343
Birebent R, Drubay D, Alves Costa Silva C, Marmorino F, Vitali G, Piccinno G, Hurtado Y, Bonato A, Belluomini L, Messaoudene M, Routy B, Fidelle M, Zalcman G, Mazieres J, Audigier-Valette C, Moro-Sibilot D, Goldwasser F, Scherpereel A, Pegliasco H, Ghiringhelli F, Reni A, Barlesi F, Albiges L, Planchard D, Martinez S, Besse B, Segata N, Cremolini C, Zitvogel L, Iebba V, Derosa L (2025) Surrogate markers of intestinal dysfunction associated with survival in advanced cancers. Oncoimmunology, 14(1):2484880, doi:10.1080/2162402X.2025.2484880.
http://www.ncbi.nlm.nih.gov/pubmed/40189749