Latest publications of CIBIO affiliates (last updated on May 1st, 2026)
El Mouali Y, Tawk C, Huang KD, Sivapornnukul P, Mengoni C, Segata N, Strowig T (2026) Biogeography-associated emergence of enhanced oxygen tolerance in the abundant human gut commensal Segatella copri. Cell Host Microbe, doi:10.1016/j.chom.2026.04.006.
http://www.ncbi.nlm.nih.gov/pubmed/42097142
Dohlman AB, Mjelle R, Wood HM, Jiang K, Shumate A, Lee I, Piccinno G, Serna G, Yakubu AR, Nuciforo P, Quirke P, Huttenhower C, Segata N, Meyerson M (2026) Biodiversity and biogeography of the multi-kingdom cancer microbiome. Cell, doi:10.1016/j.cell.2026.04.015.
http://www.ncbi.nlm.nih.gov/pubmed/42092351
Yu XA, Strachan CR, Herbold CW, Lang M, Gasche C, Makristathis A, Segata N, Pollak S, Tett A, Polz MF (2026) Genome-wide sweeps create ecological units in the human gut microbiome. Nature, doi:10.1038/s41586-026-10476-w.
http://www.ncbi.nlm.nih.gov/pubmed/42092154
Gabardi A, Gurrieri E, Carradori G, Tarantino D, D'Agostino VG (2026) Predicting Recombinant mRNA Loading into Extracellular Vesicles: Insights from CD81 Fusion Constructs. Int J Mol Sci, 27(8), doi:10.3390/ijms27083484.
http://www.ncbi.nlm.nih.gov/pubmed/42074128
Umbach A, Santini A, Bulcaen M, Guidone D, Maule G, Arosio D, Carrozzo I, Ciciani M, Brugnara E, Ramalho A, Vermeulen F, Galietta LJV, Carlon MS, Cereseto A (2026) Functional correction of the untreatable Sci Transl Med, 18(846):eadw8886, doi:10.1126/scitranslmed.adw8886.
http://www.ncbi.nlm.nih.gov/pubmed/42018671
Marini M, Iseppi M, Quintarelli S, Tedoldi F, Ravelli F, Bonmassari R, Arbustini E (2026) The Natural History of Autosomal Recessive Atrial Dilated Cardiomyopathy Associated with Mutation of Natriuretic Peptide Precursor a. Europace, doi:10.1093/europace/euag090.
http://www.ncbi.nlm.nih.gov/pubmed/42015515
Greco M, Klim J, De Wulf P (2026) Keeping it centered: decoding the activities that regulate yeast histone H3 variant Cse4 and confine it to centromeres. Front Cell Dev Biol, 14:1782273, doi:10.3389/fcell.2026.1782273.
http://www.ncbi.nlm.nih.gov/pubmed/41993598
Menzella F, Berti A, Cestaro W, Bosi A, Munari S, Gialdini F, Scandiuzzi Piovesan T, Cottini M, Lombardi C, Corsi L, De Corso E (2026) Dual Remission in Patients with Moderate-to-Severe Asthma and CRSwNP Treated with Dupilumab: A 24-Month Real-World Study. J Clin Med, 15(7), doi:10.3390/jcm15072787.
http://www.ncbi.nlm.nih.gov/pubmed/41977087
Bartolomei L, Pretto B, Brugnara S, Sontacchi A, Dassi V, Bousrih A, Damaggio C, Flangini F, Bisio A, Ciribilli Y (2026) p53 Isoforms as Modifiers of the p53-Dependent Responses: A Hidden Code? Cancers (Basel), 18(7), doi:10.3390/cancers18071057.
http://www.ncbi.nlm.nih.gov/pubmed/41976280
Valverde G, Sarhan MS, Cook R, Rota-Stabelli O, Adriaenssens EM, Zink A, Maixner F (2026) An ancient genome of Streptococcus pyogenes from a pre-Columbian Bolivian mummy. Nat Commun, doi:10.1038/s41467-026-71603-9.
http://www.ncbi.nlm.nih.gov/pubmed/41974680
Tomasoni D, Paris A, Visintainer R, Cook KD, Chen A, Figueroa I, Thomas VA, Marchetti L (2026) Predicting Aberrant Fc-fusion Protein Pharmacokinetics from In Silico Structural Properties and Physiologically Based Pharmacokinetic (PBPK) Modeling. AAPS J, 28(3), doi:10.1208/s12248-026-01232-z.
http://www.ncbi.nlm.nih.gov/pubmed/41946860
Cantarelli M, Marmocchi E, Lunardi A, Begaj R (2026) Unmasking prostate cancer risk factors leveraging organoid technology. Gene, 996:150142, doi:10.1016/j.gene.2026.150142.
http://www.ncbi.nlm.nih.gov/pubmed/41932411
Leva G, Santomaso L, Gianesello M, Patrizi S, Ress F, Cocchini F, Antonacci C, Gianno F, Abballe L, Lago C, Pozza N, Trentini G, Cardano M, Minasi S, Buttarelli FR, Antonelli M, Pernici D, Petrucci L, Antonica F, Busarello E, Iannuzzi M, Soldano A, Tebaldi T, Miele E, Ferretti E, Tiberi L (2026) Modeling pediatric low-grade glioma heterogeneity using human forebrain organoids. Mol Cancer, doi:10.1186/s12943-026-02612-x.
http://www.ncbi.nlm.nih.gov/pubmed/41923199
Lago C, Leva G, Kool M, Miele E, Tiberi L (2026) Patient-derived ependymoma and medulloblastoma tumoroids: generation, biobanking and drug screening. Nat Protoc, doi:10.1038/s41596-026-01347-9.
http://www.ncbi.nlm.nih.gov/pubmed/41912763
Parodi C, Lettieri A, Grazioli P, Di Fede E, Grassi S, Taci E, Toscani A, Prioni S, Rebellato S, Colombo EA, Rasetti S, Cutarelli A, Mariani M, Corti S, Finelli P, Prinetti A, Fazio G, Selicorni A, Conti L, Gervasini C, Massa V (2026) Lithium ameliorates neural differentiation restoring cell death balance in Cornelia de Lange syndrome 2D and 3D models. Cell Death Discov, 12(1), doi:10.1038/s41420-026-03085-z.
http://www.ncbi.nlm.nih.gov/pubmed/41904182
Babiloni-Chust I, Donato L, Sartori S, Carl M, Zerti D, Rinaldi C, Flati V, Feligioni M, D'Angelo R, Maccarone R, Poggi L (2026) Oxidative Stress Signaling and Regenerative Responses in a Larval Zebrafish Model of Retinal Light Damage. Antioxidants (Basel), 15(3), doi:10.3390/antiox15030348.
http://www.ncbi.nlm.nih.gov/pubmed/41897494
Tehrani AF, Khadka A, Furlan B, Whalen M, Biboy J, Massidda O, Vollmer W, Boll JM (2026) Peptidoglycan DD-peptidases have distinct activities that impact fitness of mBio, 17(4):e0007226, doi:10.1128/mbio.00072-26.
http://www.ncbi.nlm.nih.gov/pubmed/41870135
Kyritsis A, Beta RA, Scutelnic D, Stravokefalou V, Del Vescovo V, Arsenopoulou ZV, Papikinos K, Grasso M, Fontana F, Moutopoulou P, Tsiporis A, Samiotaki M, Panayotou G, Denti MA, Balatsos NA (2026) Mutual feedback regulation between Poly(A)-specific ribonuclease (PARN) and cognate microRNAs. Life Sci Alliance, 9(5), doi:10.26508/lsa.202503341.
http://www.ncbi.nlm.nih.gov/pubmed/41825960
Magnano GC, Glerean M, Dall'Acqua S, Abrami M, Larese Filon F, Carton F, Malatesta M, Calderan L, Galvan A, Voinovich D, Hasa D (2026) Enhanced transdermal delivery of [6]-Gingerol via Co-Administration of Acmella oleracea and Zingiber officinale lipophilic extracts. Int J Pharm, 695:126745, doi:10.1016/j.ijpharm.2026.126745.
http://www.ncbi.nlm.nih.gov/pubmed/41819387
Moiseyenko A, Antonello G, Schonhoff AM, Boktor JC, Long K, Dirks B, Oguienko AD, Winnett AV, Simpson P, Daeizadeh D, Ismagilov RF, Krajmalnik-Brown R, Segata N, Waldron LD, Mazmanian SK (2026) Faecalibacterium prausnitzii, depleted in the Parkinson's disease microbiome, improves motor deficits in α-synuclein overexpressing mice. NPJ Parkinsons Dis, 12(1), doi:10.1038/s41531-026-01287-x.
http://www.ncbi.nlm.nih.gov/pubmed/41786774
Baschirotto C, Venturelli M, Pedrinolla A (2026) Feasibility of high intensity exercise training in people with dementia and Mild Cognitive Impairment: a systematic review. BMC Geriatr, 26(1), doi:10.1186/s12877-026-07020-w.
http://www.ncbi.nlm.nih.gov/pubmed/41781921
Montaldo C, Cimini E, Tartaglia E, Antonioli M, Bordoni V, Notari S, Notarangelo M, Torchia E, Canarutto G, Piazza S, D'Agostino VG, Mazzotta V, Marchioni L, Antinori A, Agrati C, Strippoli R (2026) Proteomic profiling of circulating extracellular vesicles from COVID-19 patients and their impact on innate Vdelta2 T-cell response. Front Immunol, 17:1748398, doi:10.3389/fimmu.2026.1748398.
http://www.ncbi.nlm.nih.gov/pubmed/41756302
Piccinno G, Asnicar F (2026) Advanced computational analysis in metagenomic studies to support precision medicine. Clin Microbiol Infect, doi:10.1016/j.cmi.2026.02.018.
http://www.ncbi.nlm.nih.gov/pubmed/41748019
Lin Y, Kouraki A, Cheetham NJ, Louca P, Bowyer RC, Pope R, Asnicar F, Zhang X, Visconti A, Falchi M, Spector TD, Segata N, Valdes AM, Menni C (2026) Gut microbiome composition and function reflect socioeconomic deprivation. NPJ Biofilms Microbiomes, 12(1), doi:10.1038/s41522-026-00917-9.
http://www.ncbi.nlm.nih.gov/pubmed/41741460
Caserta S, Pera A (2026) Editorial: Exploring immune memory dynamics in chronic antigen exposure and disease progression: implications for immunotherapy. Front Immunol, 17:1769061, doi:10.3389/fimmu.2026.1769061.
http://www.ncbi.nlm.nih.gov/pubmed/41737200
Gallina GD, Lanzillotta M, Maggioni S, Cariddi A, Danè G, Bayındır Akbaş AN, Ates A, Berti A, Brunetta E, Cefle A, Chiara E, Conticini E, Cottin V, Delvino P, Fagni F, Kart Bayram GS, Karadağ Ö, Moroni G, Moiseev S, Monti S, Öğüt TS, Novikov P, Padoan R, Iorio L, Davanzo F, Tesi M, Quartuccio L, Yazici A, Matucci-Cerinic M, Dagna L, Moroni LSTOP-GPA Study Group
, (2026) Clinical outcomes of subglottic stenosis in granulomatosis with polyangiitis: results of an international multicentre observational study. Rheumatology (Oxford), 65(3), doi:10.1093/rheumatology/keag107.
http://www.ncbi.nlm.nih.gov/pubmed/41734284
Lin YT, Graells T, Sayols-Baixeras S, Dekkers KF, Schillemans T, Baldanzi G, Wuopio J, Nielsen N, Eklund AC, Holm JB, Nielsen HB, Bergström G, Smith JG, Malinovschi A, Engström G, Orho-Melander M, Fall T, Ärnlöv J (2026) Association between the gut microbiota and estimated glomerular filtration rate in two Swedish population-based cohorts. Kidney Int, 109(5):1004-1013, doi:10.1016/j.kint.2026.01.021.
http://www.ncbi.nlm.nih.gov/pubmed/41724378
Hamadou MH, Alunno L, Peroni D, Pancher M, Mazza F, Venturelli T, Belli R, Dassi E, Romanel A, Inga A (2026) Polysomal Profiling Coupled to Allele-Specific Proteomics Reveals an EIF4H TranSNP Allele Possessing Higher mRNA Translation Potential. Mol Cell Proteomics, 25(3):101535, doi:10.1016/j.mcpro.2026.101535.
http://www.ncbi.nlm.nih.gov/pubmed/41722779
Fioretti PV, Roccuzzo M, Saccon E, Pennuto M, Basso M (2026) High Content In Vitro Survival Assay of Cortical Neurons. Bio Protoc, 16(3):e5582, doi:10.21769/BioProtoc.5582.
http://www.ncbi.nlm.nih.gov/pubmed/41675986
Marchesin M, Dalfovo D, Romanel A (2026) CLISGen: A Comprehensive Resource of SNP Genotypes for Human Cell Lines. J Mol Biol, doi:10.1016/j.jmb.2026.169681.
http://www.ncbi.nlm.nih.gov/pubmed/41655835
Di Girolamo D, Di Cicco E, Miro C, Murolo M, Nappi A, Cicatiello AG, Sagliocchi S, Acampora L, Restolfer F, Ferraro J, Sol S, Boncimino F, Isma J, Neel VA, Porcelli T, Blainpain C, Mandinova A, Dentice M (2026) Thyroid hormone inactivation sustains cancer stem cell maintenance and tumorigenesis in basal cell carcinoma. J Invest Dermatol, doi:10.1016/j.jid.2026.01.025.
http://www.ncbi.nlm.nih.gov/pubmed/41644085
Miller G, Lloyd-Davies Sánchez DJ, González Martínez J, Justin AW, Lancaster MA, Guglielmi L (2026) Organizers in a dish: Modeling human CNS morphogenesis. Dev Cell, 61(2):240-258, doi:10.1016/j.devcel.2026.01.003.
http://www.ncbi.nlm.nih.gov/pubmed/41643664
Morandi-Raikova A, Cumplido-Mayoral A, Mayer U (2026) Novel object recognition in the dorsomedial and ventral hippocampus of young domestic chicks (Gallus gallus). Brain Struct Funct, 231(2):21, doi:10.1007/s00429-026-03078-9.
http://www.ncbi.nlm.nih.gov/pubmed/41627482
Rambaldelli G, Asghar S, Venturi G, Zacchini F, Serra M, Giovannini C, Gramantieri L, Bernini M, Inga A, Dassi E, Montanaro L (2026) Corrigendum to < 'Characterization of small nucleolar RNA retaining transcripts in human normal and cancer cells'> <[Non-coding RNA Research vol. 13 (2025) 153-161]>. Noncoding RNA Res, 17:160, doi:10.1016/j.ncrna.2026.01.002.
http://www.ncbi.nlm.nih.gov/pubmed/41625540
Serafini MM, Midali M, Grumelli G, Cutarelli A, Marinovich M, Conti L, Viviani B (2026) Transcript-protein discrepancy of glutamatergic receptor subunits in human iPSC-derived neurons: Implications for neurotoxicity testing. Toxicol Lett, 417:111834, doi:10.1016/j.toxlet.2026.111834.
http://www.ncbi.nlm.nih.gov/pubmed/41592671
Zaccaria C, Malkoç A, Auslender I, Heydari Y, Canossa M, Vignoli B, Pavesi L (2026) Investigation of synaptic connectivity in functional in vitro neuronal assemblies. Cell Rep Methods, 6(1):101265, doi:10.1016/j.crmeth.2025.101265.
http://www.ncbi.nlm.nih.gov/pubmed/41592533
Marini M, Iseppi M, Quintarelli S, Tedoldi F, Ravelli F, Bonmassari R, Arbustini E (2026) Autosomal Recessive Atrial Dilated Cardiomyopathy Due to J Cardiovasc Dev Dis, 13(1), doi:10.3390/jcdd13010037.
http://www.ncbi.nlm.nih.gov/pubmed/41590864
Ferrero G, Mastrocola R, Tarallo S, Pardini B, Scheijen J, van de Waarenburg M, Gallo G, Chatziioannou AC, Robinot N, Keski-Rahkonen P, Piccinno G, Segata N, Aglago EK, Hughes DJ, Jenab M, Schalkwijk CG, Naccarati A (2026) Integrative analyses of dicarbonyls and advanced glycation end-products with multiomic profiles across tissue, plasma and stool samples reveal methylglyoxal accumulation in colon cancer. Free Radic Biol Med, 246:518-530, doi:10.1016/j.freeradbiomed.2026.01.034.
http://www.ncbi.nlm.nih.gov/pubmed/41579975
Vutera Cuda A, Bajaj S, Manara V, Bellosta P (2026) Noc1 downregulation induces nucleolar stress and upregulates p53 isoforms, with a robust increase of the truncated p53E isoform in Drosophila wing discs. G3 (Bethesda), 16(3), doi:10.1093/g3journal/jkaf313.
http://www.ncbi.nlm.nih.gov/pubmed/41533679
Asnicar F, Manghi P, Fackelmann G, Baldanzi G, Bakker E, Ricci L, Piccinno G, Piperni E, Mladenovic K, Amati F, Arrè A, Ganesh S, Giordano F, Davies R, Wolf J, Bermingham KM, Berry SE, Spector TD, Segata N (2026) Gut micro-organisms associated with health, nutrition and dietary interventions. Nature, 650(8101):450-458, doi:10.1038/s41586-025-09854-7.
http://www.ncbi.nlm.nih.gov/pubmed/41372407
Groza P, Kumari K, Esteva-Socias M, Schott J, Bhattarai DP, Sajkowska JJ, Dasgupta R, Peula C, Destefanis E, Williams C, Marchand V, Wikström P, Wiberg R, Campos AB, Gilthorpe JD, Pop B, Mateus A, Motorin Y, Dassi E, Petzold K, Tuorto F, Aguilo F (2026) Fibrillarin-dependent 2'-O-methylation modulates RPS28 ribosome incorporation and oncogenic translation. Cancer Lett, 639:218124, doi:10.1016/j.canlet.2025.218124.
http://www.ncbi.nlm.nih.gov/pubmed/41260515
Basso M, Marchioretti C, Zito S, Zuccaro E, Pennuto M (2026) Androgen receptor and its coregulators in sex-biased diseases. Trends Mol Med, 32(4):399-415, doi:10.1016/j.molmed.2025.10.005.
http://www.ncbi.nlm.nih.gov/pubmed/41233252
Columbro SF, Tortarolo M, Re Cecconi AD, Piccirillo R, Bendotti C, Biasini E, Pasetto L, Bonetto V (2026) Beneficial effects of synthetic torpor in a fast-progressing mouse model of amyotrophic lateral sclerosis. Exp Neurol, 396:115521, doi:10.1016/j.expneurol.2025.115521.
http://www.ncbi.nlm.nih.gov/pubmed/41135686
Trentini G, Cazzanelli G, Lolli G (2026) Protein glycosylation and synaptic transmission: brain glycogen keeps them separated. Brain, 149(2):439-446, doi:10.1093/brain/awaf396.
http://www.ncbi.nlm.nih.gov/pubmed/41108069
Fioretti PV, Barbieri A, Migazzi A, Bressan D, Grassano M, Donini L, Roccuzzo M, Torrieri MC, Conci F, Ferracci E, Invernizzi S, Bowden KM, Bacchetti F, Cappelli S, Peroni D, Belli R, Pancher M, Mugoni V, Scarduelli G, Gianesello M, Pasetto L, Canarutto G, Carra S, Soldano A, Bisio A, Robbiati S, Valentini C, Nardella C, Piazza S, D'Agostino VG, Quattrone A, Sleiman S, Whitfield JR, Soucek L, Vignoli B, Viero G, Tiberi L, Zippo A, Demichelis F, Bonetto V, Milanese M, Buratti E, Verde F, Ticozzi N, Calvo A, Ratti A, Shaw PJ, Terenzio M, Chiacchiera F, Pennuto M, Basso M (2026) MYC-driven gliosis impairs neuron-glia communication in amyotrophic lateral sclerosis. Brain, 149(5):1604-1622, doi:10.1093/brain/awaf360.
http://www.ncbi.nlm.nih.gov/pubmed/41004427
Viola LM, Moretto M, Zigiotto L, Tambalo S, Annicchiarico L, Venturini M, Jovicich J, Sarubbo S (2026) Mapping the Functional Boundaries of the Speech Articulation Network Using Positive and Negative Direct Electrical Stimulation With Resting-State Functional MRI. Neurosurgery, 98(3):577-587, doi:10.1227/neu.0000000000003613.
http://www.ncbi.nlm.nih.gov/pubmed/40709938
Plakhova V, Battistella I, Martínez-Rojas VA, Marchioretto M, Arosio D, Masello L, Conti L, Musio C (2026) Unveiling the effect of curcumin on ion channels of SBMA motoneuron-derived cells and human IPSC-derived neurons: initial electrophysiological findings. Eur Biophys J, 55(2):175-186, doi:10.1007/s00249-025-01780-w.
http://www.ncbi.nlm.nih.gov/pubmed/40624383
Zigiotto L, Venturini R, Coletta L, Venturini M, Dal Monte D, Vavassori L, Corsini F, Annicchiarico L, Avesani P, Papagno C, Sarubbo S (2026) Maximizing Tumor Resection and Managing Cognitive Attentional Outcomes: Measures of Impact of Awake Surgery in Glioma Treatment. Neurosurgery, 98(2):365-375, doi:10.1227/neu.0000000000003591.
http://www.ncbi.nlm.nih.gov/pubmed/40539789