Latest publications of CIBIO affiliates (last updated on September 1st, 2024)
Prodi E, Corbellari R, Ghezzi L, Ciambellotti S, Catastini JE, Rappuoli M, Rotta G, Sakic I, Weiss T, Weller M, Pellegrino C, Manz MG, Neri D, De Luca R (2024) Tripokin: A multi-specific immunocytokine for cancer immunotherapy. Int J Cancer, doi:10.1002/ijc.35145.
http://www.ncbi.nlm.nih.gov/pubmed/39177452
Mancin L, Rollo I, Golzato D, Segata N, Petri C, Pengue L, Vergani L, Cassone N, Corsini A, Mota JF, Sut S, Dall'Acqua S, Paoli A (2024) Short-Term Cocoa Supplementation Influences Microbiota Composition and Serum Markers of Lipid Metabolism in Elite Male Soccer Players. Int J Sport Nutr Exerc Metab, doi:10.1123/ijsnem.2024-0012.
http://www.ncbi.nlm.nih.gov/pubmed/39117304
Valdes AM, Louca P, Visconti A, Asnicar F, Bermingham K, Nogal A, Wong K, Michelotti GA, Wolf J, Segata N, Spector TD, Berry SE, Falchi M, Menni C (2024) Vitamin A carotenoids, but not retinoids, mediate the impact of a healthy diet on gut microbial diversity. BMC Med, 22(1):321, doi:10.1186/s12916-024-03543-4.
http://www.ncbi.nlm.nih.gov/pubmed/39113058
Tsiami F, Lago C, Pozza N, Piccioni F, Zhao X, Lülsberg F, Root DE, Tiberi L, Kool M, Schittenhelm J, Bandopadhayay P, Segal RA, Tabatabai G, Merk DJ (2024) Genome-wide CRISPR-Cas9 knockout screens identify DNMT1 as a druggable dependency in sonic hedgehog medulloblastoma. Acta Neuropathol Commun, 12(1):125, doi:10.1186/s40478-024-01831-x.
http://www.ncbi.nlm.nih.gov/pubmed/39107797
Rossetto D, Cvjetan N, Walde P, Mansy SS (2024) Protocellular Heme and Iron-Sulfur Clusters. Acc Chem Res, 57(16):2293-2302, doi:10.1021/acs.accounts.4c00254.
http://www.ncbi.nlm.nih.gov/pubmed/39099316
Maines E, Temporin G, Fedrizzi M, Pasqualini A, Junior Masnata L, Campomori A, Iodice A, Piccoli G, Soffiati M, Franceschi R, Urru SAM (2024) Formulation and clinical evaluation of carbidopa/levodopa oral solution for the treatment of sepiapterin reductase deficiency. Eur J Pharm Biopharm, doi:10.1016/j.ejpb.2024.114429.
http://www.ncbi.nlm.nih.gov/pubmed/39097116
De Filippis F, Valentino V, Yap M, Cabrera-Rubio R, Barcenilla C, Carlino N, Cobo-Díaz JF, Quijada NM, Calvete-Torre I, Ruas-Madiedo P, Sabater C, Sequino G, Pasolli E, Wagner M, Margolles A, Segata N, Álvarez-Ordóñez A, Cotter PD, Ercolini D (2024) Microbiome mapping in dairy industry reveals new species and genes for probiotic and bioprotective activities. NPJ Biofilms Microbiomes, 10(1):67, doi:10.1038/s41522-024-00541-5.
http://www.ncbi.nlm.nih.gov/pubmed/39095404
Falla M, van Veelen MJ, Falk M, Weiss EM, Roveri G, Masè M, Weber B, Randi A, Brugger H, Hüfner K, Strapazzon G (2024) Effect of oxygen supplementation on cognitive performance among HEMS providers after acute exposure to altitude: the HEMS II randomized clinical trial. Scand J Trauma Resusc Emerg Med, 32(1):65, doi:10.1186/s13049-024-01238-6.
http://www.ncbi.nlm.nih.gov/pubmed/39075543
Lombardi C, Menzella F, Berti A (2024) Very long-term data on patients with severe eosinophilic asthma treated with mepolizumab: a case series. Drugs Context, 13, doi:10.7573/dic.2024-4-2.
http://www.ncbi.nlm.nih.gov/pubmed/39072303
Corral-Jara KF, Skírnisdóttir S, Knobloch S, Briem H, Cobo-Díaz JF, Carlino N, Bergsten P, Armanini F, Asnicar F, Pinto F, Alvarez-Ordóñez A, Segata N, Marteinsson VÞ (2024) Inter-facility characterization of bacteria in seafood processing plants: Exploring potential reservoirs of spoilage organisms and the resistome. Heliyon, 10(13):e33866, doi:10.1016/j.heliyon.2024.e33866.
http://www.ncbi.nlm.nih.gov/pubmed/39071556
Romito E, Battistella I, Plakhova V, Paplekaj A, Forastieri C, Toffolo E, Musio C, Conti L, Battaglioli E, Rusconi F (2024) A comprehensive protocol for efficient differentiation of human NPCs into electrically competent neurons. J Neurosci Methods, 410:110225, doi:10.1016/j.jneumeth.2024.110225.
http://www.ncbi.nlm.nih.gov/pubmed/39053772
Maines E, Franceschi R, Rivieri F, Piccoli G, Schulte B, Hoffmann J, Bordugo A, Rodella G, Teofoli F, Vincenzi M, Soffiati M, Camilot M (2024) Biochemical Pattern of Methylmalonyl-CoA Epimerase Deficiency Identified in Newborn Screening: A Case Report. Int J Neonatal Screen, 10(3), doi:10.3390/ijns10030053.
http://www.ncbi.nlm.nih.gov/pubmed/39051409
Contenti J, Guo Y, Larcher M, Mirabal-Ortega L, Rouleau M, Irondelle M, Tiroille V, Mazzu A, Duranton-Tanneur V, Pedeutour F, Ben-Sahra I, Lago C, Leva G, Tiberi L, Robert G, Pouponnot C, Bost F, Mazure NM (2024) HIF-1 inactivation empowers HIF-2 to drive hypoxia adaptation in aggressive forms of medulloblastoma. Cell Death Discov, 10(1):338, doi:10.1038/s41420-024-02100-5.
http://www.ncbi.nlm.nih.gov/pubmed/39048564
Aguilo F, Dassi E (2024) Editorial: Translational control in cancer. NAR Cancer, 6(3):zcae031, doi:10.1093/narcan/zcae031.
http://www.ncbi.nlm.nih.gov/pubmed/39045152
Cheng Z, Fobian SF, Gurrieri E, Amin M, D'Agostino VG, Falahati M, Zalba S, Debets R, Garrido MJ, Saeed M, Seynhaeve ALB, Balcioglu HE, Ten Hagen TLM (2024) Lipid-based nanosystems: the next generation of cancer immune therapy. J Hematol Oncol, 17(1):53, doi:10.1186/s13045-024-01574-1.
http://www.ncbi.nlm.nih.gov/pubmed/39030582
Sighel D, Destefanis E, Quattrone A (2024) Therapeutic strategies to target the epitranscriptomic machinery. Curr Opin Genet Dev, 87:102230, doi:10.1016/j.gde.2024.102230.
http://www.ncbi.nlm.nih.gov/pubmed/39024774
Montani C, Balasco L, Pagani M, Alvino FG, Barsotti N, de Guzman AE, Galbusera A, de Felice A, Nickl-Jockschat TK, Migliarini S, Casarosa S, Lau P, Mattioni L, Pasqualetti M, Provenzano G, Bozzi Y, Lombardo MV, Gozzi A (2024) Sex-biasing influence of autism-associated Sci Adv, 10(28):eadg1421, doi:10.1126/sciadv.adg1421.
http://www.ncbi.nlm.nih.gov/pubmed/38996019
Detassis S, Precazzini F, Brentari I, Ruffilli R, Ress C, Maglione A, Pernagallo S, Denti MA (2024) SA-ODG platform: a semi-automated and PCR-free method to analyse microRNAs in solid tissues. Analyst, 149(15):3891-3899, doi:10.1039/d4an00783b.
http://www.ncbi.nlm.nih.gov/pubmed/38994789
Piperni E, Nguyen LH, Manghi P, Kim H, Pasolli E, Andreu-Sánchez S, Arrè A, Bermingham KM, Blanco-Míguez A, Manara S, Valles-Colomer M, Bakker E, Busonero F, Davies R, Fiorillo E, Giordano F, Hadjigeorgiou G, Leeming ER, Lobina M, Masala M, Maschio A, McIver LJ, Pala M, Pitzalis M, Wolf J, Fu J, Zhernakova A, Cacciò SM, Cucca F, Berry SE, Ercolini D, Chan AT, Huttenhower C, Spector TD, Segata N, Asnicar F (2024) Intestinal Blastocystis is linked to healthier diets and more favorable cardiometabolic outcomes in 56,989 individuals from 32 countries. Cell, 187(17):4554-4570.e18, doi:10.1016/j.cell.2024.06.018.
http://www.ncbi.nlm.nih.gov/pubmed/38981480
Ciani Y, Nardella C, Demichelis F (2024) Casting a wider net: The clinical potential of EV transcriptomics in multi-analyte liquid biopsy. Cancer Cell, 42(7):1160-1162, doi:10.1016/j.ccell.2024.06.007.
http://www.ncbi.nlm.nih.gov/pubmed/38981437
Pangrazzi L, Provenzano G, Treccani G, Balasco L (2024) Editorial: Toward an understanding of neurodevelopmental disorders: novel insights from molecular, behavioural and neuroinflammatory mechanisms. Front Psychiatry, 15:1444783, doi:10.3389/fpsyt.2024.1444783.
http://www.ncbi.nlm.nih.gov/pubmed/38979502
Andreazzoli M, Argenton F, Bertolucci C, Finazzi D, Gabellini C, Mione M, Pistocchi A, Santoro M, Sordino P, Cavalieri V (2024) Zebrafish from the Alps to Sicily: The 4th Italian Zebrafish Meeting in Palermo. Zebrafish, 21(4):275-278, doi:10.1089/zeb.2024.0140.
http://www.ncbi.nlm.nih.gov/pubmed/38963004
Vettorato E, Verona M, Bellio G, Croci S, Filadi R, Bisio A, Spessot E, Andrighetto A, Maniglio D, Asti M, Marzaro G, Mastrotto F (2024) Development and Validation of Novel Z-360-Based Macromolecules for the Active Targeting of CCK2-R. Mol Pharm, 21(8):3848-3865, doi:10.1021/acs.molpharmaceut.4c00124.
http://www.ncbi.nlm.nih.gov/pubmed/38959127
Ferro A, Campora M, Caldara A, De Lisi D, Lorenzi M, Monteverdi S, Mihai R, Bisio A, Dipasquale M, Caffo O, Ciribilli Y (2024) Novel Treatment Strategies for Hormone Receptor (HR)-Positive, HER2-Negative Metastatic Breast Cancer. J Clin Med, 13(12), doi:10.3390/jcm13123611.
http://www.ncbi.nlm.nih.gov/pubmed/38930141
Derosa L, Iebba V, Silva CAC, Piccinno G, Wu G, Lordello L, Routy B, Zhao N, Thelemaque C, Birebent R, Marmorino F, Fidelle M, Messaoudene M, Thomas AM, Zalcman G, Friard S, Mazieres J, Audigier-Valette C, Sibilot DM, Goldwasser F, Scherpereel A, Pegliasco H, Ghiringhelli F, Bouchard N, Sow C, Darik I, Zoppi S, Ly P, Reni A, Daillère R, Deutsch E, Lee KA, Bolte LA, Björk JR, Weersma RK, Barlesi F, Padilha L, Finzel A, Isaksen ML, Escudier B, Albiges L, Planchard D, André F, Cremolini C, Martinez S, Besse B, Zhao L, Segata N, Wojcik J, Kroemer G, Zitvogel L (2024) Custom scoring based on ecological topology of gut microbiota associated with cancer immunotherapy outcome. Cell, 187(13):3373-3389.e16, doi:10.1016/j.cell.2024.05.029.
http://www.ncbi.nlm.nih.gov/pubmed/38906102
Detassis S, Precazzini F, Grasso M, Del Vescovo V, Maines F, Caffo O, Campomenosi P, Denti MA (2024) Plasma microRNA Signature as Companion Diagnostic for Abiraterone Acetate Treatment in Metastatic Castration-Resistant Prostate Cancer: A Pilot Study. Int J Mol Sci, 25(11), doi:10.3390/ijms25115573.
http://www.ncbi.nlm.nih.gov/pubmed/38891761
Rotta G, Puca E, Cazzamalli S, Neri D, Dakhel Plaza S (2024) Cytokine Biopharmaceuticals with "Activity-on-Demand" for Cancer Therapy. Bioconjug Chem, 35(8):1075-1088, doi:10.1021/acs.bioconjchem.4c00187.
http://www.ncbi.nlm.nih.gov/pubmed/38885090
Sevegnani M, Lama A, Girardi F, Hess MW, Castelo MP, Pichler I, Biressi S, Piccoli G (2024) Parkin R274W mutation affects muscle and mitochondrial physiology. Biochim Biophys Acta Mol Basis Dis, 1870(7):167302, doi:10.1016/j.bbadis.2024.167302.
http://www.ncbi.nlm.nih.gov/pubmed/38878834
Antonaci M, Kerr A, Lawrence M, Lorenzini F, Narwade N, Paka C, Wulf AM (2024) Neural crest development and disorders: from patient to model system and back again - the NEUcrest conference. Biol Open, 13(6), doi:10.1242/bio.060530.
http://www.ncbi.nlm.nih.gov/pubmed/38874999
Palumbo M, Modena R, Bortolan L, Skafidas S, Callovini A, Savoldelli A, Gilli F, Fornasiero A, Schena F, Pellegrini B, Zoppirolli C (2024) Effects of a similar amount of regular non-structured or competitive physical activity across late adulthood: a cross-sectional study. Front Sports Act Living, 6:1416080, doi:10.3389/fspor.2024.1416080.
http://www.ncbi.nlm.nih.gov/pubmed/38873229
Dubois L, Valles-Colomer M, Ponsero A, Helve O, Andersson S, Kolho KL, Asnicar F, Korpela K, Salonen A, Segata N, de Vos WM (2024) Paternal and induced gut microbiota seeding complement mother-to-infant transmission. Cell Host Microbe, 32(6):1011-1024.e4, doi:10.1016/j.chom.2024.05.004.
http://www.ncbi.nlm.nih.gov/pubmed/38870892
Bettin N, Querido E, Gialdini I, Grupelli GP, Goretti E, Cantarelli M, Andolfato M, Soror E, Sontacchi A, Jurikova K, Chartrand P, Cusanelli E (2024) TERRA transcripts localize at long telomeres to regulate telomerase access to chromosome ends. Sci Adv, 10(24):eadk4387, doi:10.1126/sciadv.adk4387.
http://www.ncbi.nlm.nih.gov/pubmed/38865460
Lombardi C, Comberiati P, Ridolo E, Cottini M, Yacoub MR, Casagrande S, Riccò M, Bottazzoli M, Berti A (2024) Anti-IL-5 Pathway Agents in Eosinophilic-Associated Disorders Across the Lifespan. Drugs, 84(6):661-684, doi:10.1007/s40265-024-02037-0.
http://www.ncbi.nlm.nih.gov/pubmed/38849701
Moretto M, Luciani BF, Zigiotto L, Saviola F, Tambalo S, Cabalo DG, Annicchiarico L, Venturini M, Jovicich J, Sarubbo S (2024) Resting State Functional Networks in Gliomas: Validation With Direct Electric Stimulation of a New Tool for Planning Brain Resections. Neurosurgery, doi:10.1227/neu.0000000000003012.
http://www.ncbi.nlm.nih.gov/pubmed/38836617
Marchesini M, Gherli A, Simoncini E, Tor LMD, Montanaro A, Thongon N, Vento F, Liverani C, Cerretani E, D'Antuono A, Pagliaro L, Zamponi R, Spadazzi C, Follini E, Cambò B, Giaimo M, Falco A, Sammarelli G, Todaro G, Bonomini S, Adami V, Piazza S, Corbo C, Lorusso B, Mezzasoma F, Lagrasta CAM, Martelli MP, La Starza R, Cuneo A, Aversa F, Mecucci C, Quaini F, Colla S, Roti G (2024) Orthogonal proteogenomic analysis identifies the druggable PA2G4-MYC axis in 3q26 AML. Nat Commun, 15(1):4739, doi:10.1038/s41467-024-48953-3.
http://www.ncbi.nlm.nih.gov/pubmed/38834613
Cammas A, Desprairies A, Dassi E, Millevoi S (2024) The shaping of mRNA translation plasticity by RNA G-quadruplexes in cancer progression and therapy resistance. NAR Cancer, 6(2):zcae025, doi:10.1093/narcan/zcae025.
http://www.ncbi.nlm.nih.gov/pubmed/38828391
de Antonellis P, Ferrucci V, Miceli M, Bibbo F, Asadzadeh F, Gorini F, Mattivi A, Boccia A, Russo R, Andolfo I, Lasorsa VA, Cantalupo S, Fusco G, Viscardi M, Brandi S, Cerino P, Monaco V, Choi DR, Cheong JH, Iolascon A, Amente S, Monti M, Fava LL, Capasso M, Kim HY, Zollo M (2024) Targeting ATP2B1 impairs PI3K/Akt/FOXO signaling and reduces SARS-COV-2 infection and replication. EMBO Rep, 25(7):2974-3007, doi:10.1038/s44319-024-00164-z.
http://www.ncbi.nlm.nih.gov/pubmed/38816514
Selma-Royo M, Ricci L, Golzato D, Servais C, Nabinejad A, Armanini F, Asnicar F, Pinto F, Tamburini S, Segata N (2024) Draft genome sequences of multiple bacterial strains isolated from human feces. Microbiol Resour Announc, 13(7):e0030724, doi:10.1128/mra.00307-24.
http://www.ncbi.nlm.nih.gov/pubmed/38809053
Del Piano F, Almroth BC, Lama A, Piccolo G, Addeo NF, Paciello O, Martino G, Esposito S, Mercogliano R, Pirozzi C, Meli R, Ferrante MC (2024) Subchronic oral exposure to polystyrene microplastics affects hepatic lipid metabolism, inflammation, and oxidative balance in gilthead seabream (Sparus aurata). Ecotoxicol Environ Saf, 279:116455, doi:10.1016/j.ecoenv.2024.116455.
http://www.ncbi.nlm.nih.gov/pubmed/38772140
Masè M, Cristoforetti A, Pelloni S, Ravelli F (2024) Systematic in-silico evaluation of fibrosis effects on re-entrant wave dynamics in atrial tissue. Sci Rep, 14(1):11427, doi:10.1038/s41598-024-62002-5.
http://www.ncbi.nlm.nih.gov/pubmed/38763959
Marangon M, Marassi V, Roda B, Zattoni A, Reschiglian P, Mattivi F, Moio L, Ricci A, Piombino P, Segade SR, Giacosa S, Slaghenaufi D, Versari A, Vrhovsek U, Ugliano M, De Iseppi A, Mayr Marangon C, Curioni A (2024) Comprehensive analysis of colloid formation, distribution, and properties of monovarietal red wines using asymmetrical flow field-flow fractionation with online multidetection. Food Res Int, 187:114414, doi:10.1016/j.foodres.2024.114414.
http://www.ncbi.nlm.nih.gov/pubmed/38763663
Valentini S, Fedrizzi T, Demichelis F, Romanel A (2024) Correction: PaCBAM: fast and scalable processing of whole exome and targeted sequencing data. BMC Genomics, 25(1):463, doi:10.1186/s12864-024-10348-5.
http://www.ncbi.nlm.nih.gov/pubmed/38741054
Dufresnes C, Ghielmi S, Halpern B, Martínez-Freiría F, Mebert K, Jelić D, Crnobrnja-Isailović J, Gippner S, Jablonski D, Joger U, Laddaga L, Petrovan S, Tomović L, Vörös J, İğci N, Kariş M, Zinenko O, Ursenbacher S (2024) Phylogenomic insights into the diversity and evolution of Palearctic vipers. Mol Phylogenet Evol, 197:108095, doi:10.1016/j.ympev.2024.108095.
http://www.ncbi.nlm.nih.gov/pubmed/38729384
Bulcaen M, Kortleven P, Liu RB, Maule G, Dreano E, Kelly M, Ensinck MM, Thierie S, Smits M, Ciciani M, Hatton A, Chevalier B, Ramalho AS, Casadevall I Solvas X, Debyser Z, Vermeulen F, Gijsbers R, Sermet-Gaudelus I, Cereseto A, Carlon MS (2024) Prime editing functionally corrects cystic fibrosis-causing CFTR mutations in human organoids and airway epithelial cells. Cell Rep Med, 5(5):101544, doi:10.1016/j.xcrm.2024.101544.
http://www.ncbi.nlm.nih.gov/pubmed/38697102
Koralewska N, Corradi E, Milewski MC, Masante L, Szczepanska A, Kierzek R, Figlerowicz M, Baudet ML, Kurzynska-Kokorniak A (2024) Short 2'-O-methyl/LNA oligomers as highly-selective inhibitors of miRNA production in vitro and in vivo. Nucleic Acids Res, 52(10):5804-5824, doi:10.1093/nar/gkae284.
http://www.ncbi.nlm.nih.gov/pubmed/38676942
Mangiapane G, Notarangelo M, Canarutto G, Fabbiano F, Dalla E, Degrassi M, Antoniali G, Gualandi N, De Sanctis V, Piazza S, D'Agostino VG, Tell G (2024) The DNA-repair protein APE1 participates with hnRNPA2B1 to motif-enriched and prognostic miRNA secretion. Oncogene, 43(24):1861-1876, doi:10.1038/s41388-024-03039-8.
http://www.ncbi.nlm.nih.gov/pubmed/38664500
Cai T, Tamanini I, Odorizzi K, Gallelli L, Lanzafame M, Mazzoli S, Lanzafame P, Massidda O, Palmieri A, Wagenlehner FME, Bjerklund Johansen TE, De Nunzio C (2024) The diagnostic yield of the Meares & Stamey test can be significantly improved by symptom-based patient selection and the experience of the test performer. Prostate Cancer Prostatic Dis, 27(2):300-304, doi:10.1038/s41391-024-00824-0.
http://www.ncbi.nlm.nih.gov/pubmed/38555411
Mattioni L, Barbieri A, Grigoli A, Balasco L, Bozzi Y, Provenzano G (2024) Alterations of Perineuronal Net Expression and Abnormal Social Behavior and Whisker-dependent Texture Discrimination in Mice Lacking the Autism Candidate Gene Engrailed 2. Neuroscience, 546:63-74, doi:10.1016/j.neuroscience.2024.03.023.
http://www.ncbi.nlm.nih.gov/pubmed/38537894
Vitali E, Grasso A, Schiavone ML, Trivellin G, Sobacchi C, Mione M, Mazziotti G, Lania A (2024) The direct impact of pegvisomant on osteoblast functions and bone development. J Endocrinol Invest, 47(6):1385-1394, doi:10.1007/s40618-023-02281-3.
http://www.ncbi.nlm.nih.gov/pubmed/38159174