Latest publications of CIBIO affiliates (last updated on July 1st, 2021)
Ambrosini C, Garilli F, Quattrone A (2021) Reprogramming translation for gene therapy. Prog Mol Biol Transl Sci, 182:439-476, doi:10.1016/bs.pmbts.2021.01.028.
http://www.ncbi.nlm.nih.gov/pubmed/34175050
Bauer J, Cuvelier N, Ragab N, Simon-Keller K, Nitzki F, Geyer N, Botermann DS, Elmer DP, Rosenberger A, Rando TA, Biressi S, Fagin JA, Saur D, Dullin C, Schildhaus HU, Schulz-Schaeffer W, Aberger F, Uhmann A, Hahn H (2021) Context-dependent modulation of aggressiveness of pediatric tumors by individual oncogenic RAS isoforms. Oncogene, doi:10.1038/s41388-021-01904-4.
http://www.ncbi.nlm.nih.gov/pubmed/34172934
Ballabio C, Gianesello M, Lago C, Okonechnikov K, Anderle M, Aiello G, Antonica F, Zhang T, Gianno F, Giangaspero F, Hassan BA, Pfister SM, Tiberi L (2021) Notch1 switches progenitor competence in inducing medulloblastoma. Sci Adv, 7(26), doi:10.1126/sciadv.abd2781.
http://www.ncbi.nlm.nih.gov/pubmed/34162555
Masè M, Ravelli F (2021) Understanding the effects of heartbeat irregularity on ventricular function in human atrial fibrillation: simulation models may help to untie the knot. Europace, doi:10.1093/europace/euab143.
http://www.ncbi.nlm.nih.gov/pubmed/34160027
Galeaz C, Totis C, Bisio A (2021) Radiation Resistance: A Matter of Transcription Factors. Front Oncol, 11:662840, doi:10.3389/fonc.2021.662840.
http://www.ncbi.nlm.nih.gov/pubmed/34141616
Casaro MB, Thomas AM, Mendes E, Fukumori C, Ribeiro WR, Oliveira FA, Crisma AR, Murata GM, Bizzarro B, Sá-Nunes A, Setubal JC, Mayer MPA, Martins FS, Vieira AT, Antiorio ATFB, Tavares-de-Lima W, Camara NOS, Curi R, Dias-Neto E, Ferreira CM (2021) A probiotic has differential effects on allergic airway inflammation in A/J and C57BL/6 mice and is correlated with the gut microbiome. Microbiome, 9(1):134, doi:10.1186/s40168-021-01081-2.
http://www.ncbi.nlm.nih.gov/pubmed/34112246
Beltran H, Demichelis F (2021) Therapy considerations in neuroendocrine prostate cancer: what next? Endocr Relat Cancer, doi:10.1530/ERC-21-0140.
http://www.ncbi.nlm.nih.gov/pubmed/34111024
Zhang T, Liu T, Mora N, Guegan J, Bertrand M, Contreras X, Hansen AH, Streicher C, Anderle M, Danda N, Tiberi L, Hippenmeyer S, Hassan BA (2021) Generation of excitatory and inhibitory neurons from common progenitors via Notch signaling in the cerebellum. Cell Rep, 35(10):109208, doi:10.1016/j.celrep.2021.109208.
http://www.ncbi.nlm.nih.gov/pubmed/34107249
Mazidi M, Valdes AM, Ordovas JM, Hall WL, Pujol JC, Wolf J, Hadjigeorgiou G, Segata N, Sattar N, Koivula R, Spector TD, Franks PW, Berry SE (2021) Meal-induced inflammation: postprandial insights from the Personalised REsponses to DIetary Composition Trial (PREDICT) study in 1000 participants. Am J Clin Nutr, doi:10.1093/ajcn/nqab132.
http://www.ncbi.nlm.nih.gov/pubmed/34100082
Eilers W, Denti MA (2021) Delivery of Antisense RNA Therapeutics: Turning Negative Results Into a Positive Development. Nucleic Acid Ther, 31(3):183-184, doi:10.1089/nat.2021.0028.
http://www.ncbi.nlm.nih.gov/pubmed/34097476
Nodari A, Scambi I, Peroni D, Calabria E, Benati D, Mannucci S, Manfredi M, Frontini A, Visonà S, Bozzato A, Sbarbati A, Schena F, Marengo E, Krampera M, Galiè M (2021) Interferon regulatory factor 7 impairs cellular metabolism in aging adipose-derived stromal cells. J Cell Sci, 134(11), doi:10.1242/jcs.256230.
http://www.ncbi.nlm.nih.gov/pubmed/34096605
Biferali B, Bianconi V, Perez DF, Kronawitter SP, Marullo F, Maggio R, Santini T, Polverino F, Biagioni S, Summa V, Toniatti C, Pasini D, Stricker S, Di Fabio R, Chiacchiera F, Peruzzi G, Mozzetta C (2021) Prdm16-mediated H3K9 methylation controls fibro-adipogenic progenitors identity during skeletal muscle repair. Sci Adv, 7(23), doi:10.1126/sciadv.abd9371.
http://www.ncbi.nlm.nih.gov/pubmed/34078594
Silvestro S, Chiricosta L, Gugliandolo A, Iori R, Rollin P, Perenzoni D, Mattivi F, Bramanti P, Mazzon E (2021) The Moringin/α-CD Pretreatment Induces Neuroprotection in an In Vitro Model of Alzheimer's Disease: A Transcriptomic Study. Curr Issues Mol Biol, 43(1):197-214, doi:10.3390/cimb43010017.
http://www.ncbi.nlm.nih.gov/pubmed/34073287
Löffler RJG, Hanczyc MM, Gorecki J (2021) A Perfect Plastic Material for Studies on Self-Propelled Motion on the Water Surface. Molecules, 26(11), doi:10.3390/molecules26113116.
http://www.ncbi.nlm.nih.gov/pubmed/34071048
Cutarelli A, Martínez-Rojas VA, Tata A, Battistella I, Rossi D, Arosio D, Musio C, Conti L (2021) A Monolayer System for the Efficient Generation of Motor Neuron Progenitors and Functional Motor Neurons from Human Pluripotent Stem Cells. Cells, 10(5), doi:10.3390/cells10051127.
http://www.ncbi.nlm.nih.gov/pubmed/34066970
Gaudioso G, Marzorati G, Faccenda F, Weil T, Lunelli F, Cardinaletti G, Marino G, Olivotto I, Parisi G, Tibaldi E, Tuohy KM, Fava F (2021) Processed Animal Proteins from Insect and Poultry By-Products in a Fish Meal-Free Diet for Rainbow Trout: Impact on Intestinal Microbiota and Inflammatory Markers. Int J Mol Sci, 22(11), doi:10.3390/ijms22115454.
http://www.ncbi.nlm.nih.gov/pubmed/34064267
Ataollahi N, Broseghini M, Ferreira FF, Susana A, Pizzato M, Scardi P (2021) Effect of High-Energy Milling on the Dissolution of Anti-HIV Drug Efavirenz in Different Solvents. ACS Omega, 6(19):12647-12659, doi:10.1021/acsomega.1c00712.
http://www.ncbi.nlm.nih.gov/pubmed/34056416
Cottini M, Licini A, Lombardi C, Bagnasco D, Comberiati P, Berti A (2021) Small airway dysfunction and poor asthma control: a dangerous liaison. Clin Mol Allergy, 19(1):7, doi:10.1186/s12948-021-00147-8.
http://www.ncbi.nlm.nih.gov/pubmed/34051816
Tett A, Pasolli E, Masetti G, Ercolini D, Segata N (2021) Prevotella diversity, niches and interactions with the human host. Nat Rev Microbiol, doi:10.1038/s41579-021-00559-y.
http://www.ncbi.nlm.nih.gov/pubmed/34050328
Capone A, Naro C, Bianco M, De Bardi M, Noël F, Macchi P, Battistini L, Soumelis V, Volpe E, Sette C (2021) Systems analysis of human T helper17 cell differentiation uncovers distinct time-regulated transcriptional modules. iScience, 24(5):102492, doi:10.1016/j.isci.2021.102492.
http://www.ncbi.nlm.nih.gov/pubmed/34036250
Burigotto M, Fava LL (2021) The PIDDosome: centrosome guardian and backup on the DNA damage response. Mol Cell Oncol, 8(3):1893625, doi:10.1080/23723556.2021.1893625.
http://www.ncbi.nlm.nih.gov/pubmed/34027036
Simone R, Javad F, Emmett W, Wilkins OG, Almeida FL, Barahona-Torres N, Zareba-Paslawska J, Ehteramyan M, Zuccotti P, Modelska A, Siva K, Virdi GS, Mitchell JS, Harley J, Kay VA, Hondhamuni G, Trabzuni D, Ryten M, Wray S, Preza E, Kia DA, Pittman A, Ferrari R, Manzoni C, Lees A, Hardy JA, Denti MA, Quattrone A, Patani R, Svenningsson P, Warner TT, Plagnol V, Ule J, de Silva R (2021) MIR-NATs repress MAPT translation and aid proteostasis in neurodegeneration. Nature, 594(7861):117-123, doi:10.1038/s41586-021-03556-6.
http://www.ncbi.nlm.nih.gov/pubmed/34012113
Liu D, Augello MA, Grbesa I, Prandi D, Liu Y, Shoag JE, Karnes RJ, Trock BJ, Klein EA, Den RB, Demichelis F, Davicioni E, Sboner A, Barbieri CE (2021) Tumor subtype defines distinct pathways of molecular and clinical progression in primary prostate cancer. J Clin Invest, 131(10), doi:10.1172/JCI147878.
http://www.ncbi.nlm.nih.gov/pubmed/33998599
Berti A, Bortolotti R, Dipasquale M, Kinspergher S, Prokop L, Grandi G, Inchiostro S, Paolazzi G, Caffo O, Veccia A (2021) Meta-analysis of immune-related adverse events in phase 3 clinical trials assessing immune checkpoint inhibitors for lung cancer. Crit Rev Oncol Hematol, 162:103351, doi:10.1016/j.critrevonc.2021.103351.
http://www.ncbi.nlm.nih.gov/pubmed/33989769
Wibowo MC, Yang Z, Borry M, Hübner A, Huang KD, Tierney BT, Zimmerman S, Barajas-Olmos F, Contreras-Cubas C, García-Ortiz H, Martínez-Hernández A, Luber JM, Kirstahler P, Blohm T, Smiley FE, Arnold R, Ballal SA, Pamp SJ, Russ J, Maixner F, Rota-Stabelli O, Segata N, Reinhard K, Orozco L, Warinner C, Snow M, LeBlanc S, Kostic AD (2021) Reconstruction of ancient microbial genomes from the human gut. Nature, 594(7862):234-239, doi:10.1038/s41586-021-03532-0.
http://www.ncbi.nlm.nih.gov/pubmed/33981035
Herviou P, Le Bras M, Dumas L, Hieblot C, Gilhodes J, Cioci G, Hugnot JP, Ameadan A, Guillonneau F, Dassi E, Cammas A, Millevoi S (2021) Author Correction: hnRNP H/F drive RNA G-quadruplex-mediated translation linked to genomic instability and therapy resistance in glioblastoma. Nat Commun, 12(1):2929, doi:10.1038/s41467-021-23484-3.
http://www.ncbi.nlm.nih.gov/pubmed/33980840
Goubet AG, Wheeler R, Fluckiger A, Qu B, Lemaître F, Iribarren K, Mondragón L, Tidjani Alou M, Pizzato E, Durand S, Derosa L, Aprahamian F, Bossut N, Moya-Nilges M, Derrien D, Chen G, Leduc M, Joseph A, Pons N, Le Chatelier E, Segata N, Yonekura S, Iebba V, Kepp O, Raoult D, André F, Kroemer G, Boneca IG, Zitvogel L, Daillère R (2021) Multifaceted modes of action of the anticancer probiotic Enterococcus hirae. Cell Death Differ, doi:10.1038/s41418-021-00753-8.
http://www.ncbi.nlm.nih.gov/pubmed/33976389
Louca P, Nogal A, Wells PM, Asnicar F, Wolf J, Steves CJ, Spector TD, Segata N, Berry SE, Valdes AM, Menni C (2021) Gut microbiome diversity and composition is associated with hypertension in women. J Hypertens, doi:10.1097/HJH.0000000000002878.
http://www.ncbi.nlm.nih.gov/pubmed/33973959
Terrisse S, Derosa L, Iebba V, Ghiringhelli F, Vaz-Luis I, Kroemer G, Fidelle M, Christodoulidis S, Segata N, Thomas AM, Martin AL, Sirven A, Everhard S, Aprahamian F, Nirmalathasan N, Aarnoutse R, Smidt M, Ziemons J, Caldas C, Loibl S, Denkert C, Durand S, Iglesias C, Pietrantonio F, Routy B, André F, Pasolli E, Delaloge S, Zitvogel L (2021) Intestinal microbiota influences clinical outcome and side effects of early breast cancer treatment. Cell Death Differ, doi:10.1038/s41418-021-00784-1.
http://www.ncbi.nlm.nih.gov/pubmed/33963313
Pasquardini L, Roncador A, Prusakova V, Vanzetti L, Potrich C, Lunelli L, Pederzolli C, Iannotta S, Macchi P, Dirè S (2021) Functionalization of TiO Colloids Surf B Biointerfaces, 204:111787, doi:10.1016/j.colsurfb.2021.111787.
http://www.ncbi.nlm.nih.gov/pubmed/33962371
Lunardi A, Barbareschi M, Carbone FG, Morelli L, Brunelli M, Fortuna N, Genovesi S, Alaimo A (2021) TRPM8 protein expression in hormone naïve local and lymph node metastatic prostate cancer. Pathologica, 113(2):95-101, doi:10.32074/1591-951X-262.
http://www.ncbi.nlm.nih.gov/pubmed/33955429
Beghini F, McIver LJ, Blanco-Míguez A, Dubois L, Asnicar F, Maharjan S, Mailyan A, Manghi P, Scholz M, Thomas AM, Valles-Colomer M, Weingart G, Zhang Y, Zolfo M, Huttenhower C, Franzosa EA, Segata N (2021) Integrating taxonomic, functional, and strain-level profiling of diverse microbial communities with bioBakery 3. Elife, 10, doi:10.7554/eLife.65088.
http://www.ncbi.nlm.nih.gov/pubmed/33944776
Pasini L, Notarangelo M, Vagheggini A, Burgio MA, Crinò L, Chiadini E, Prochowski AI, Delmonte A, Ulivi P, D'Agostino VG (2021) Unveiling mutational dynamics in non-small cell lung cancer patients by quantitative EGFR profiling in vesicular RNA. Mol Oncol, doi:10.1002/1878-0261.12976.
http://www.ncbi.nlm.nih.gov/pubmed/33942501
Nodari A, Scambi I, Peroni D, Calabria E, Benati D, Mannucci S, Manfredi M, Frontini A, Visonà S, Bozzato A, Sbarbati A, Schena F, Marengo E, Krampera M, Galiè M (2021) Interferon Regulatory Factor 7 impairs cellular metabolism with age in adipose-derived stromal cells. J Cell Sci, doi:10.1242/jcs.256230.
http://www.ncbi.nlm.nih.gov/pubmed/33929530
Fulgenzio C, Massari M, Traversa G, Da Cas R, Ferrante G, Aschbacher R, Moser V, Pagani E, Vestri AR, Massidda O, Kurotschka PK (2021) Impact of Prior Antibiotic Use in Primary Care on Antibiotics (Basel), 10(4), doi:10.3390/antibiotics10040451.
http://www.ncbi.nlm.nih.gov/pubmed/33923682
Fochesato A, Simoni G, Reali F, Giordano G, Domenici E, Marchetti L (2021) A Retrospective Analysis of the COVID-19 Pandemic Evolution in Italy. Biology (Basel), 10(4), doi:10.3390/biology10040311.
http://www.ncbi.nlm.nih.gov/pubmed/33917920
Sighel D, Notarangelo M, Aibara S, Re A, Ricci G, Guida M, Soldano A, Adami V, Ambrosini C, Broso F, Rosatti EF, Longhi S, Buccarelli M, D'Alessandris QG, Giannetti S, Pacioni S, Ricci-Vitiani L, Rorbach J, Pallini R, Roulland S, Amunts A, Mancini I, Modelska A, Quattrone A (2021) Inhibition of mitochondrial translation suppresses glioblastoma stem cell growth. Cell Rep, 35(4):109024, doi:10.1016/j.celrep.2021.109024.
http://www.ncbi.nlm.nih.gov/pubmed/33910005
Rosa A, Pye VE, Graham C, Muir L, Seow J, Ng KW, Cook NJ, Rees-Spear C, Parker E, Dos Santos MS, Rosadas C, Susana A, Rhys H, Nans A, Masino L, Roustan C, Christodoulou E, Ulferts R, Wrobel AG, Short CE, Fertleman M, Sanders RW, Heaney J, Spyer M, Kjær S, Riddell A, Malim MH, Beale R, MacRae JI, Taylor GP, Nastouli E, van Gils MJ, Rosenthal PB, Pizzato M, McClure MO, Tedder RS, Kassiotis G, McCoy LE, Doores KJ, Cherepanov P (2021) SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity. Sci Adv, 7(22), doi:10.1126/sciadv.abg7607.
http://www.ncbi.nlm.nih.gov/pubmed/33888467
Adami V, Homer N, Utz N, Lippens S, Rappoport JZ, Fernandez-Rodriguez J (2021) An international survey of Training Needs and Career Paths of Core Facility Staff. J Biomol Tech, 32(1):1-9, doi:10.7171/jbt.21-3201-002.
http://www.ncbi.nlm.nih.gov/pubmed/33880077
Cereseto A, Cradick TJ, Davies K (2021) Base Editors Flex Sights on Sickle-Cell Disease. CRISPR J, 4(2):166-168, doi:10.1089/crispr.2021.29125.kda.
http://www.ncbi.nlm.nih.gov/pubmed/33876950
Maines E, Franceschi R, Martinelli D, Soli F, Lepri FR, Piccoli G, Soffiati M (2021) Hypoglycemia due to PI3K/AKT/mTOR signaling pathway defects: two novel cases and review of the literature. Hormones (Athens), doi:10.1007/s42000-021-00287-1.
http://www.ncbi.nlm.nih.gov/pubmed/33876391
Pischedda F, Cirnaru MD, Ponzoni L, Sandre M, Biosa A, Carrion MP, Marin O, Morari M, Pan L, Greggio E, Bandopadhyay R, Sala M, Piccoli G (2021) LRRK2 G2019S kinase activity triggers neurotoxic NSF aggregation. Brain, 144(5):1509-1525, doi:10.1093/brain/awab073.
http://www.ncbi.nlm.nih.gov/pubmed/33876242
Low DY, Micheau P, Koistinen VM, Hanhineva K, Abrankó L, Rodriguez-Mateos A, da Silva AB, van Poucke C, Almeida C, Andres-Lacueva C, Rai DK, Capanoglu E, Tomás Barberán FA, Mattivi F, Schmidt G, Gürdeniz G, Valentová K, Bresciani L, Petrásková L, Dragsted LO, Philo M, Ulaszewska M, Mena P, González-Domínguez R, Garcia-Villalba R, Kamiloglu S, de Pascual-Teresa S, Durand S, Wiczkowski W, Bronze MR, Stanstrup J, Manach C (2021) Data sharing in PredRet for accurate prediction of retention time: Application to plant food bioactive compounds. Food Chem, 357:129757, doi:10.1016/j.foodchem.2021.129757.
http://www.ncbi.nlm.nih.gov/pubmed/33872868
Ghetti S, Burigotto M, Mattivi A, Magnani G, Casini A, Bianchi A, Cereseto A, Fava LL (2021) CRISPR/Cas9 ribonucleoprotein-mediated knockin generation in hTERT-RPE1 cells. STAR Protoc, 2(2):100407, doi:10.1016/j.xpro.2021.100407.
http://www.ncbi.nlm.nih.gov/pubmed/33855309
Migazzi A, Scaramuzzino C, Anderson EN, Tripathy D, Hernández IH, Grant RA, Roccuzzo M, Tosatto L, Virlogeux A, Zuccato C, Caricasole A, Ratovitski T, Ross CA, Pandey UB, Lucas JJ, Saudou F, Pennuto M, Basso M (2021) Huntingtin-mediated axonal transport requires arginine methylation by PRMT6. Cell Rep, 35(2):108980, doi:10.1016/j.celrep.2021.108980.
http://www.ncbi.nlm.nih.gov/pubmed/33852844
Ramos H, Soares MIL, Silva J, Raimundo L, Calheiros J, Gomes C, Reis F, Monteiro FA, Nunes C, Reis S, Bosco B, Piazza S, Domingues L, Chlapek P, Vlcek P, Fabian P, Rajado AT, Carvalho ATP, Veselska R, Inga A, Pinho E Melo TMVD, Saraiva L (2021) A selective p53 activator and anticancer agent to improve colorectal cancer therapy. Cell Rep, 35(2):108982, doi:10.1016/j.celrep.2021.108982.
http://www.ncbi.nlm.nih.gov/pubmed/33852837
Ubbiali D, Orlando M, Kovačič M, Iacobucci C, Semrau MS, Bajc G, Fortuna S, Ilc G, Medagli B, Oloketuyi S, Storici P, Sinz A, Grandori R, de Marco A (2021) An anti-HER2 nanobody binds to its antigen HER2 via two independent paratopes. Int J Biol Macromol, 182:502-511, doi:10.1016/j.ijbiomac.2021.04.032.
http://www.ncbi.nlm.nih.gov/pubmed/33848543
Thomas AM, Asnicar F, Kroemer G, Segata N (2021) Genes Encoding Microbial Acyl Coenzyme A Binding Protein/Diazepam-Binding Inhibitor Orthologs Are Rare in the Human Gut Microbiome and Show No Links to Obesity. Appl Environ Microbiol, 87(12):e0047121, doi:10.1128/AEM.00471-21.
http://www.ncbi.nlm.nih.gov/pubmed/33837018
Fantinatti BEA, Perez ES, Zanella BTT, Valente JS, de Paula TG, Mareco EA, Carvalho RF, Piazza S, Denti MA, Dal-Pai-Silva M (2021) Integrative microRNAome analysis of skeletal muscle of Colossoma macropomum (tambaqui), Piaractus mesopotamicus (pacu), and the hybrid tambacu, based on next-generation sequencing data. BMC Genomics, 22(1):237, doi:10.1186/s12864-021-07513-5.
http://www.ncbi.nlm.nih.gov/pubmed/33823787
Hammond SM, Aartsma-Rus A, Alves S, Borgos SE, Buijsen RAM, Collin RWJ, Covello G, Denti MA, Desviat LR, Echevarría L, Foged C, Gaina G, Garanto A, Goyenvalle AT, Guzowska M, Holodnuka I, Jones DR, Krause S, Lehto T, Montolio M, Van Roon-Mom W, Arechavala-Gomeza V (2021) Delivery of oligonucleotide-based therapeutics: challenges and opportunities. EMBO Mol Med, 13(4):e13243, doi:10.15252/emmm.202013243.
http://www.ncbi.nlm.nih.gov/pubmed/33821570
Cottini M, Lombardi C, Berti APrimary Care Physicians, ATS Province of Bergamo, Italy, (2021) Obesity is a Major Risk Factor for Hospitalization in Community-Managed COVID-19 Pneumonia. Mayo Clin Proc, 96(4):921-931, doi:10.1016/j.mayocp.2021.01.021.
http://www.ncbi.nlm.nih.gov/pubmed/33814092
Bertocchi A, Carloni S, Ravenda PS, Bertalot G, Spadoni I, Lo Cascio A, Gandini S, Lizier M, Braga D, Asnicar F, Segata N, Klaver C, Brescia P, Rossi E, Anselmo A, Guglietta S, Maroli A, Spaggiari P, Tarazona N, Cervantes A, Marsoni S, Lazzari L, Jodice MG, Luise C, Erreni M, Pece S, Di Fiore PP, Viale G, Spinelli A, Pozzi C, Penna G, Rescigno M (2021) Gut vascular barrier impairment leads to intestinal bacteria dissemination and colorectal cancer metastasis to liver. Cancer Cell, 39(5):708-724.e11, doi:10.1016/j.ccell.2021.03.004.
http://www.ncbi.nlm.nih.gov/pubmed/33798472
Hanson BT, Dimitri Kits K, Löffler J, Burrichter AG, Fiedler A, Denger K, Frommeyer B, Herbold CW, Rattei T, Karcher N, Segata N, Schleheck D, Loy A (2021) Sulfoquinovose is a select nutrient of prominent bacteria and a source of hydrogen sulfide in the human gut. ISME J, doi:10.1038/s41396-021-00968-0.
http://www.ncbi.nlm.nih.gov/pubmed/33790426
Wirbel J, Zych K, Essex M, Karcher N, Kartal E, Salazar G, Bork P, Sunagawa S, Zeller G (2021) Microbiome meta-analysis and cross-disease comparison enabled by the SIAMCAT machine learning toolbox. Genome Biol, 22(1):93, doi:10.1186/s13059-021-02306-1.
http://www.ncbi.nlm.nih.gov/pubmed/33785070
Gao Y, Chen S, Halene S, Tebaldi T (2021) Transcriptome-wide quantification of double-stranded RNAs in live mouse tissues by dsRIP-Seq. STAR Protoc, 2(1):100366, doi:10.1016/j.xpro.2021.100366.
http://www.ncbi.nlm.nih.gov/pubmed/33778776
Mangiapane G, Parolini I, Conte K, Malfatti MC, Corsi J, Sanchez M, Pietrantoni A, D'Agostino VG, Tell G (2021) Enzymatically active apurinic/apyrimidinic endodeoxyribonuclease 1 is released by mammalian cells through exosomes. J Biol Chem, doi:10.1016/j.jbc.2021.100569.
http://www.ncbi.nlm.nih.gov/pubmed/33753167
Pollini D, Loffredo R, Maniscalco F, Cardano M, Micaelli M, Bonomo I, Licata NV, Peroni D, Tomaszewska W, Rossi A, Crippa V, Dassi E, Viero G, Quattrone A, Poletti A, Conti L, Provenzani A (2021) Multilayer and MATR3-dependent regulation of mRNAs maintains pluripotency in human induced pluripotent stem cells. iScience, 24(3):102197, doi:10.1016/j.isci.2021.102197.
http://www.ncbi.nlm.nih.gov/pubmed/33733063
Asnicar F, Leeming ER, Dimidi E, Mazidi M, Franks PW, Al Khatib H, Valdes AM, Davies R, Bakker E, Francis L, Chan A, Gibson R, Hadjigeorgiou G, Wolf J, Spector TD, Segata N, Berry SE (2021) Blue poo: impact of gut transit time on the gut microbiome using a novel marker. Gut, doi:10.1136/gutjnl-2020-323877.
http://www.ncbi.nlm.nih.gov/pubmed/33722860
Fryk E, Olausson J, Mossberg K, Strindberg L, Schmelz M, Brogren H, Gan LM, Piazza S, Provenzani A, Becattini B, Lind L, Solinas G, Jansson PA (2021) Hyperinsulinemia and insulin resistance in the obese may develop as part of a homeostatic response to elevated free fatty acids: A mechanistic case-control and a population-based cohort study. EBioMedicine, 65:103264, doi:10.1016/j.ebiom.2021.103264.
http://www.ncbi.nlm.nih.gov/pubmed/33712379
Song Y, Shan L, Gbyli R, Liu W, Strowig T, Patel A, Fu X, Wang X, Xu ML, Gao Y, Qin A, Bruscia EM, Tebaldi T, Biancon G, Mamillapalli P, Urbonas D, Eynon E, Gonzalez DG, Chen J, Krause DS, Alderman J, Halene S, Flavell RA (2021) Combined liver-cytokine humanization comes to the rescue of circulating human red blood cells. Science, 371(6533):1019-1025, doi:10.1126/science.abe2485.
http://www.ncbi.nlm.nih.gov/pubmed/33674488
Juríková K, De Wulf P, Cusanelli E (2021) Nuclear Periphery and Telomere Maintenance: TERRA Joins the Stage. Trends Genet, 37(7):608-611, doi:10.1016/j.tig.2021.02.003.
http://www.ncbi.nlm.nih.gov/pubmed/33663806
Verhagen H, Alonso-Andicoberry C, Assunção R, Cavaliere F, Eneroth H, Hoekstra J, Koulouris S, Kouroumalis A, Lorenzetti S, Mantovani A, Menozzi D, Nauta M, Poulsen M, Rubert J, Siani A, Sirot V, Spaggiari G, Thomsen ST, Trevisan M, Cozzini P (2021) Risk-benefit in food safety and nutrition - Outcome of the 2019 Parma Summer School. Food Res Int, 141:110073, doi:10.1016/j.foodres.2020.110073.
http://www.ncbi.nlm.nih.gov/pubmed/33641961
Pavani G, Fabiano A, Laurent M, Amor F, Cantelli E, Chalumeau A, Maule G, Tachtsidi A, Concordet JP, Cereseto A, Mavilio F, Ferrari G, Miccio A, Amendola M (2021) Correction of β-thalassemia by CRISPR/Cas9 editing of the α-globin locus in human hematopoietic stem cells. Blood Adv, 5(5):1137-1153, doi:10.1182/bloodadvances.2020001996.
http://www.ncbi.nlm.nih.gov/pubmed/33635334
Corbellari R, Stringhini M, Mock J, Ongaro T, Villa A, Neri D, De Luca R (2021) A Novel Antibody-IL15 Fusion Protein Selectively Localizes to Tumors, Synergizes with TNF-based Immunocytokine, and Inhibits Metastasis. Mol Cancer Ther, 20(5):859-871, doi:10.1158/1535-7163.MCT-20-0853.
http://www.ncbi.nlm.nih.gov/pubmed/33632875
Cottini M, Lombardi C, Berti A, Comberiati P (2021) Small-airway dysfunction in paediatric asthma. Curr Opin Allergy Clin Immunol, 21(2):128-134, doi:10.1097/ACI.0000000000000728.
http://www.ncbi.nlm.nih.gov/pubmed/33620881
Zhou X, Ulaszewska MM, De Gobba C, Rinnan Å, Poulsen MW, Chen J, Mattivi F, Hedegaard RV, Skibsted LH, Dragsted LO (2021) New Advanced Glycation End Products Observed in Rat Urine by Untargeted Metabolomics after Feeding with Heat-Treated Skimmed Milk Powder. Mol Nutr Food Res, 65(7):e2001049, doi:10.1002/mnfr.202001049.
http://www.ncbi.nlm.nih.gov/pubmed/33559951
Ravera S, Esposito A, Degan P, Caicci F, Manni L, Liguori A, Bisio A, Iobbi V, Schito A, Traverso CE, Panfoli I (2021) The diterpene Manool extracted from Salvia tingitana lowers free radical production in retinal rod outer segments by inhibiting the extramitochondrial F Cell Biochem Funct, 39(4):528-535, doi:10.1002/cbf.3618.
http://www.ncbi.nlm.nih.gov/pubmed/33472276
Destefanis E, Avşar G, Groza P, Romitelli A, Torrini S, Pir P, Conticello SG, Aguilo F, Dassi E (2021) A mark of disease: how mRNA modifications shape genetic and acquired pathologies. RNA, 27(4):367-389, doi:10.1261/rna.077271.120.
http://www.ncbi.nlm.nih.gov/pubmed/33376192
Persi E, Wolf YI, Horn D, Ruppin E, Demichelis F, Gatenby RA, Gillies RJ, Koonin EV (2021) Publisher Correction: Mutation-selection balance and compensatory mechanisms in tumour evolution. Nat Rev Genet, 22(4):263, doi:10.1038/s41576-020-00313-9.
http://www.ncbi.nlm.nih.gov/pubmed/33318707
Corrado A, Aceto R, Silvestri R, Dell'Anno I, Ricci B, Miglietta S, Romei C, Giovannoni R, Poliseno L, Evangelista M, Vitiello M, Cipollini M, Garritano S, Giusti L, Zallocco L, Elisei R, Landi S, Gemignani F (2021) Pro64His (rs4644) Polymorphism Within Galectin-3 Is a Risk Factor of Differentiated Thyroid Carcinoma and Affects the Transcriptome of Thyrocytes Engineered via CRISPR/Cas9 System. Thyroid, doi:10.1089/thy.2020.0366.
http://www.ncbi.nlm.nih.gov/pubmed/33308024
Dumas L, Herviou P, Dassi E, Cammas A, Millevoi S (2021) G-Quadruplexes in RNA Biology: Recent Advances and Future Directions. Trends Biochem Sci, 46(4):270-283, doi:10.1016/j.tibs.2020.11.001.
http://www.ncbi.nlm.nih.gov/pubmed/33303320
Persi E, Wolf YI, Horn D, Ruppin E, Demichelis F, Gatenby RA, Gillies RJ, Koonin EV (2021) Mutation-selection balance and compensatory mechanisms in tumour evolution. Nat Rev Genet, 22(4):251-262, doi:10.1038/s41576-020-00299-4.
http://www.ncbi.nlm.nih.gov/pubmed/33257848
Pischedda F, Piccoli G (2021) LRRK2 at the pre-synaptic site: A 16-years perspective. J Neurochem, 157(2):297-311, doi:10.1111/jnc.15240.
http://www.ncbi.nlm.nih.gov/pubmed/33206398
Martínez-Rojas VA, Jiménez-Garduño AM, Michelatti D, Tosatto L, Marchioretto M, Arosio D, Basso M, Pennuto M, Musio C (2021) ClC-2-like Chloride Current Alterations in a Cell Model of Spinal and Bulbar Muscular Atrophy, a Polyglutamine Disease. J Mol Neurosci, 71(3):662-674, doi:10.1007/s12031-020-01687-5.
http://www.ncbi.nlm.nih.gov/pubmed/32856205