Latest publications of CIBIO affiliates (last updated on April 1st, 2017)

Fedrizzi T, Meehan CJ, Grottola A, Giacobazzi E, Fregni Serpini G, Tagliazucchi S, Fabio A, Bettua C, Bertorelli R, De Sanctis V, Rumpianesi F, Pecorari M, Jousson O, Tortoli E, Segata N (2017) Genomic characterization of Nontuberculous Mycobacteria. Sci Rep, 7:45258, doi:10.1038/srep45258.
http://www.ncbi.nlm.nih.gov/pubmed/28345639

Querin G, Martinelli I, Bertolin C, Pegoraro E, Pennuto M, Sorarù G (2017) The role of AR polyQ tract in male breast carcinoma: lesson from a SBMA case. Ann. Oncol., doi:10.1093/annonc/mdx038.
http://www.ncbi.nlm.nih.gov/pubmed/28327982

Comisso E, Scarola M, Rosso M, Piazza S, Marzinotto S, Ciani Y, Orsaria M, Mariuzzi L, Schneider C, Schoeftner S, Benetti R (2017) OCT4 controls mitotic stability and inactivates the RB tumor suppressor pathway to enhance ovarian cancer aggressiveness. Oncogene, doi:10.1038/onc.2017.20.
http://www.ncbi.nlm.nih.gov/pubmed/28319064

Soares J, Espadinha M, Raimundo L, Ramos H, Gomes AS, Gomes S, Loureiro JB, Inga A, Reis F, Gomes C, Santos MM, Saraiva L (2017) DIMP53-1: A novel small-molecule dual inhibitor of p53-MDM2/X interactions with multifunctional p53-dependent anticancer properties. Mol Oncol, doi:10.1002/1878-0261.12051.
http://www.ncbi.nlm.nih.gov/pubmed/28296148

Vignoli B, Canossa M (2017) Glioactive ATP controls BDNF recycling in cortical astrocytes. Commun Integr Biol, 10(1):e1277296, doi:10.1080/19420889.2016.1277296.
http://www.ncbi.nlm.nih.gov/pubmed/28289489

Godfrey C, Desviat LR, Smedsrød B, Piétri-Rouxel F, Denti MA, Disterer P, Lorain S, Nogales-Gadea G, Sardone V, Anwar R, El Andaloussi S, Lehto T, Khoo B, Brolin C, van Roon-Mom WM, Goyenvalle A, Aartsma-Rus A, Arechavala-Gomeza V (2017) Delivery is key: lessons learnt from developing splice-switching antisense therapies. EMBO Mol Med, doi:10.15252/emmm.201607199.
http://www.ncbi.nlm.nih.gov/pubmed/28289078

Mansy SS (2017) Protocells: Non-living predators. Nat Chem, 9(2):107-108, doi:10.1038/nchem.2725.
http://www.ncbi.nlm.nih.gov/pubmed/28282047

Sasi M, Vignoli B, Canossa M, Blum R (2017) Neurobiology of local and intercellular BDNF signaling. Pflugers Arch., doi:10.1007/s00424-017-1964-4.
http://www.ncbi.nlm.nih.gov/pubmed/28280960

Lentini R, Martín NY, Forlin M, Belmonte L, Fontana J, Cornella M, Martini L, Tamburini S, Bentley WE, Jousson O, Mansy SS (2017) Two-Way Chemical Communication between Artificial and Natural Cells. ACS Cent Sci, 3(2):117-123, doi:10.1021/acscentsci.6b00330.
http://www.ncbi.nlm.nih.gov/pubmed/28280778

Ghensi P, Bressan E, Gardin C, Ferroni L, Ruffato L, Caberlotto M, Soldini C, Zavan B (2017) Osteo Growth Induction titanium surface treatment reduces ROS production of mesenchymal stem cells increasing their osteogenic commitment. Mater Sci Eng C Mater Biol Appl, 74:389-398, doi:10.1016/j.msec.2016.12.032.
http://www.ncbi.nlm.nih.gov/pubmed/28254309

Salamin K, Eugster PJ, Jousson O, Waridel P, Grouzmann E, Monod M (2017) AoS28D, a proline-Xaa carboxypeptidase secreted by Aspergillus oryzae. Appl. Microbiol. Biotechnol., doi:10.1007/s00253-017-8186-8.
http://www.ncbi.nlm.nih.gov/pubmed/28229206

Strati F, Cavalieri D, Albanese D, De Felice C, Donati C, Hayek J, Jousson O, Leoncini S, Renzi D, Calabrò A, De Filippo C (2017) New evidences on the altered gut microbiota in autism spectrum disorders. Microbiome, 5(1):24, doi:10.1186/s40168-017-0242-1.
http://www.ncbi.nlm.nih.gov/pubmed/28222761

Ebner DK, Tinganelli W, Helm A, Bisio A, Yamada S, Kamada T, Shimokawa T, Durante M (2017) The Immunoregulatory Potential of Particle Radiation in Cancer Therapy. Front Immunol, 8:99, doi:10.3389/fimmu.2017.00099.
http://www.ncbi.nlm.nih.gov/pubmed/28220126

Hong TP, Carter MQ, Struffi P, Casonato S, Hao Y, Lam JS, Lory S, Jousson O (2017) Conjugative type IVb pilus recognizes lipopolysaccharide of recipient cells to initiate PAPI-1 pathogenicity island transfer in Pseudomonas aeruginosa. BMC Microbiol., 17(1):31, doi:10.1186/s12866-017-0943-4.
http://www.ncbi.nlm.nih.gov/pubmed/28173753

Truong DT, Tett A, Pasolli E, Huttenhower C, Segata N (2017) Microbial strain-level population structure and genetic diversity from metagenomes. Genome Res., doi:10.1101/gr.216242.116.
http://www.ncbi.nlm.nih.gov/pubmed/28167665

Zeng Y, Navarro P, Shirali M, Howard DM, Adams MJ, Hall LS, Clarke TK, Thomson PA, Smith BH, Murray A, Padmanabhan S, Hayward C, Boutin T, MacIntyre DJ, Lewis CM, Wray NR, Mehta D, Penninx BW, Milaneschi Y, Baune BT, Air T, Hottenga JJ, Mbarek H, Castelao E, Pistis G, Schulze TG, Streit F, Forstner AJ, Byrne EM, Martin NG, Breen G, Müller-Myhsok B, Lucae S, Kloiber S, Domenici E, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Deary IJ, Porteous DJ, Haley CS, McIntosh AM (2016) Genome-wide Regional Heritability Mapping Identifies a Locus Within the TOX2 Gene Associated With Major Depressive Disorder. Biol. Psychiatry, doi:10.1016/j.biopsych.2016.12.012.
http://www.ncbi.nlm.nih.gov/pubmed/28153336

Bellon A, Iyer A, Bridi S, Lee FC, Ovando-Vázquez C, Corradi E, Longhi S, Roccuzzo M, Strohbuecker S, Naik S, Sarkies P, Miska E, Abreu-Goodger C, Holt CE, Baudet ML (2017) miR-182 Regulates Slit2-Mediated Axon Guidance by Modulating the Local Translation of a Specific mRNA. Cell Rep, 18(5):1171-1186, doi:10.1016/j.celrep.2016.12.093.
http://www.ncbi.nlm.nih.gov/pubmed/28147273

Asnicar F, Manara S, Zolfo M, Truong DT, Scholz M, Armanini F, Ferretti P, Gorfer V, Pedrotti A, Tett A, Segata N (2016) Studying Vertical Microbiome Transmission from Mothers to Infants by Strain-Level Metagenomic Profiling. mSystems, 2(1), doi:10.1128/mSystems.00164-16.
http://www.ncbi.nlm.nih.gov/pubmed/28144631

Ferri L, Covello G, Caciotti A, Guerrini R, Denti MA, Morrone A (2016) Double-target Antisense U1snRNAs Correct Mis-splicing Due to c.639+861C>T and c.639+919G>A GLA Deep Intronic Mutations. Mol Ther Nucleic Acids, 5:e380, doi:10.1038/mtna.2016.88.
http://www.ncbi.nlm.nih.gov/pubmed/28131260

Masè M, Grasso M, Avogaro L, D'Amato E, Tessarolo F, Graffigna A, Denti MA, Ravelli F (2017) Selection of reference genes is critical for miRNA expression analysis in human cardiac tissue. A focus on atrial fibrillation. Sci Rep, 7:41127, doi:10.1038/srep41127.
http://www.ncbi.nlm.nih.gov/pubmed/28117343

Milioto C, Malena A, Maino E, Polanco MJ, Marchioretti C, Borgia D, Pereira MG, Blaauw B, Lieberman AP, Venturini R, Plebani M, Sambataro F, Vergani L, Pegoraro E, Sorarù G, Pennuto M (2017) Beta-agonist stimulation ameliorates the phenotype of spinal and bulbar muscular atrophy mice and patient-derived myotubes. Sci Rep, 7:41046, doi:10.1038/srep41046.
http://www.ncbi.nlm.nih.gov/pubmed/28117338

Bernabò P, Gaglio M, Bellamoli F, Viero G, Lencioni V (2017) DNA damage and translational response during detoxification from copper exposure in a wild population of Chironomus riparius. Chemosphere, 173:235-244, doi:10.1016/j.chemosphere.2017.01.052.
http://www.ncbi.nlm.nih.gov/pubmed/28110013

Chizzolini F, Forlin M, Yeh Martín N, Berloffa G, Cecchi D, Mansy SS (2017) Cell-Free Translation Is More Variable than Transcription. ACS Synth Biol, doi:10.1021/acssynbio.6b00250.
http://www.ncbi.nlm.nih.gov/pubmed/28100049

Allegra M, Spalletti C, Vignoli B, Azzimondi S, Busti I, Billuart P, Canossa M, Caleo M (2017) Pharmacological rescue of adult hippocampal neurogenesis in a mouse model of X-linked intellectual disability. Neurobiol. Dis., 100:75-86, doi:10.1016/j.nbd.2017.01.003.
http://www.ncbi.nlm.nih.gov/pubmed/28088401

Borgia D, Malena A, Spinazzi M, Andrea Desbats M, Salviati L, Russell AP, Miotto G, Tosatto L, Pegoraro E, Sorarù G, Pennuto M, Vergani L (2017) Increased mitophagy in the skeletal muscle of spinal and bulbar muscular atrophy patients. Hum. Mol. Genet., doi:10.1093/hmg/ddx019.
http://www.ncbi.nlm.nih.gov/pubmed/28087734

Mu P, Zhang Z, Benelli M, Karthaus WR, Hoover E, Chen CC, Wongvipat J, Ku SY, Gao D, Cao Z, Shah N, Adams EJ, Abida W, Watson PA, Prandi D, Huang CH, de Stanchina E, Lowe SW, Ellis L, Beltran H, Rubin MA, Goodrich DW, Demichelis F, Sawyers CL (2017) SOX2 promotes lineage plasticity and antiandrogen resistance in TP53- and RB1-deficient prostate cancer. Science, 355(6320):84-88, doi:10.1126/science.aah4307.
http://www.ncbi.nlm.nih.gov/pubmed/28059768

Pasetto L, Pozzi S, Castelnovo M, Basso M, Estevez AG, Fumagalli S, De Simoni MG, Castellaneta V, Bigini P, Restelli E, Chiesa R, Trojsi F, Monsurrò MR, Callea L, Malešević M, Fischer G, Freschi M, Tortarolo M, Bendotti C, Bonetto V (2017) Targeting Extracellular Cyclophilin A Reduces Neuroinflammation and Extends Survival in a Mouse Model of Amyotrophic Lateral Sclerosis. J. Neurosci., 37(6):1413-1427, doi:10.1523/JNEUROSCI.2462-16.2016.
http://www.ncbi.nlm.nih.gov/pubmed/28011744

Brázda V, Čechová J, Battistin M, Coufal J, Jagelská EB, Raimondi I, Inga A (2017) The structure formed by inverted repeats in p53 response elements determines the transactivation activity of p53 protein. Biochem. Biophys. Res. Commun., 483(1):516-521, doi:10.1016/j.bbrc.2016.12.113.
http://www.ncbi.nlm.nih.gov/pubmed/28007599

Polanco MJ, Parodi S, Piol D, Stack C, Chivet M, Contestabile A, Miranda HC, Lievens PM, Espinoza S, Jochum T, Rocchi A, Grunseich C, Gainetdinov RR, Cato AC, Lieberman AP, La Spada AR, Sambataro F, Fischbeck KH, Gozes I, Pennuto M (2016) Adenylyl cyclase activating polypeptide reduces phosphorylation and toxicity of the polyglutamine-expanded androgen receptor in spinobulbar muscular atrophy. Sci Transl Med, 8(370):370ra181, doi:10.1126/scitranslmed.aaf9526.
http://www.ncbi.nlm.nih.gov/pubmed/28003546

Bianconi I, D'Arcangelo S, Benedet M, Bailey KE, Esposito A, Piffer E, Mariotto A, Baldo E, Dinnella G, Gualdi P, Schinella M, Donati C, Jousson O (2016) Draft Genome Sequences of 40 Pseudomonas aeruginosa Clinical Strains Isolated from the Sputum of a Single Cystic Fibrosis Patient Over an 8-Year Period. Genome Announc, 4(6), doi:10.1128/genomeA.01205-16.
http://www.ncbi.nlm.nih.gov/pubmed/27979930

Mayrhofer M, Gourain V, Reischl M, Affaticati P, Jenett A, Joly JS, Benelli M, Demichelis F, Poliani PL, Sieger D, Mione M (2017) A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. Dis Model Mech, 10(1):15-28, doi:10.1242/dmm.026500.
http://www.ncbi.nlm.nih.gov/pubmed/27935819

Marsoner F, Marcatili M, Karnavas T, Bottai D, D'Agostino A, Scarone S, Conti L (2016) Generation and characterization of an induced pluripotent stem cell (iPSC) line from a patient with clozapine-resistant Schizophrenia. Stem Cell Res, 17(3):661-664, doi:10.1016/j.scr.2016.11.005.
http://www.ncbi.nlm.nih.gov/pubmed/27934603

Marcatili M, Marsoner F, D'Agostino A, Karnavas T, Bottai D, Scarone S, Conti L (2016) Establishment of an induced pluripotent stem cell (iPSC) line from a patient with Clozapine-responder Schizophrenia. Stem Cell Res, 17(3):630-633, doi:10.1016/j.scr.2016.11.009.
http://www.ncbi.nlm.nih.gov/pubmed/27934596

Cardano M, Marsoner F, Marcatili M, Karnavas T, Zasso J, Lanterna LA, Conti L (2016) Establishment of induced pluripotent stem cell (iPSC) line from 55-year old male patient with hemorrhagic Moyamoya disease. Stem Cell Res, 17(3):623-626, doi:10.1016/j.scr.2016.11.006.
http://www.ncbi.nlm.nih.gov/pubmed/27934594

Cardano M, Marsoner F, Zasso J, Marcatili M, Karnavas T, Lanterna LA, Conti L (2016) Establishment of induced pluripotent stem cell (iPSC) line from an 8-year old female patient with ischemic Moyamoya disease. Stem Cell Res, 17(3):619-622, doi:10.1016/j.scr.2016.11.007.
http://www.ncbi.nlm.nih.gov/pubmed/27934593

Bongiovanni MN, Godet J, Horrocks MH, Tosatto L, Carr AR, Wirthensohn DC, Ranasinghe RT, Lee JE, Ponjavic A, Fritz JV, Dobson CM, Klenerman D, Lee SF (2016) Multi-dimensional super-resolution imaging enables surface hydrophobicity mapping. Nat Commun, 7:13544, doi:10.1038/ncomms13544.
http://www.ncbi.nlm.nih.gov/pubmed/27929085

Re A, Waldron L, Quattrone A (2016) Control of Gene Expression by RNA Binding Protein Action on Alternative Translation Initiation Sites. PLoS Comput. Biol., 12(12):e1005198, doi:10.1371/journal.pcbi.1005198.
http://www.ncbi.nlm.nih.gov/pubmed/27923063

Soldovieri MV, Ambrosino P, Mosca I, De Maria M, Moretto E, Miceli F, Alaimo A, Iraci N, Manocchio L, Medoro A, Passafaro M, Taglialatela M (2016) Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7.2 potassium channels to phosphatidylinositol 4,5-bisphosphate. Sci Rep, 6:38167, doi:10.1038/srep38167.
http://www.ncbi.nlm.nih.gov/pubmed/27905566