Latest publications of CIBIO affiliates (last updated on April 1st, 2024)
Cai T, Tamanini I, Odorizzi K, Gallelli L, Lanzafame M, Mazzoli S, Lanzafame P, Massidda O, Palmieri A, Wagenlehner FME, Bjerklund Johansen TE, De Nunzio C (2024) The diagnostic yield of the Meares & Stamey test can be significantly improved by symptom-based patient selection and the experience of the test performer. Prostate Cancer Prostatic Dis, doi:10.1038/s41391-024-00824-0.
http://www.ncbi.nlm.nih.gov/pubmed/38555411
Blanco-Míguez A, Carloni S, Cardenas C, Dioguardi CC, Lambroia L, Capretti G, Nappo G, Fugazza A, Capogreco A, Armanini F, Asnicar F, Dubois L, Golzato D, Manghi P, Pinto F, Scuderi C, Casari E, Montorsi M, Anderloni A, Rescigno M, Repici A, Zerbi A, Peano C, Tamburini S, Rusconi R, Segata N (2024) Microbial composition associated with biliary stents in patients undergoing pancreatic resection for cancer. NPJ Biofilms Microbiomes, 10(1):35, doi:10.1038/s41522-024-00506-8.
http://www.ncbi.nlm.nih.gov/pubmed/38555334
De Koninck Y, Alonso J, Bancelin S, Béïque JC, Bélanger E, Bouchard C, Canossa M, Chaniot J, Choquet D, Crochetière MÈ, Cui N, Danglot L, De Koninck P, Devor A, Ducros M, Getz AM, Haouat M, Hernández IC, Jowett N, Keramidis I, Larivière-Loiselle C, Lavoie-Cardinal F, MacGillavry HD, Malkoç A, Mancinelli M, Marquet P, Minderler S, Moreaud M, Nägerl UV, Papanikolopoulou K, Paquet ME, Pavesi L, Perrais D, Sansonetti R, Thunemann M, Vignoli B, Yau J, Zaccaria C (2024) Understanding the nervous system: lessons from Frontiers in Neurophotonics. Neurophotonics, 11(1):014415, doi:10.1117/1.NPh.11.1.014415.
http://www.ncbi.nlm.nih.gov/pubmed/38545127
Habicher J, Sanvido I, Bühler A, Sartori S, Piccoli G, Carl M (2024) The Risk Genes for Neuropsychiatric Disorders Genes (Basel), 15(3), doi:10.3390/genes15030363.
http://www.ncbi.nlm.nih.gov/pubmed/38540422
Barros O, D'Agostino VG, Santos L, Ferreira R, Vitorino R (2024) Revisiting Multi-Omics Data to Unravel Galectins as Prognostic Factors in Head and Neck Squamous Cell Carcinoma. Biomedicines, 12(3), doi:10.3390/biomedicines12030529.
http://www.ncbi.nlm.nih.gov/pubmed/38540141
Mattioni L, Barbieri A, Grigoli A, Balasco L, Bozzi Y, Provenzano G (2024) Alterations of perineuronal net expression and abnormal social behavior and whisker-dependent texture discrimination in mice lacking the autism candidate gene Engrailed 2. Neuroscience, doi:10.1016/j.neuroscience.2024.03.023.
http://www.ncbi.nlm.nih.gov/pubmed/38537894
Ruta GV, Ciciani M, Kheir E, Gentile MD, Amistadi S, Casini A, Cereseto A (2024) Eukaryotic-driven directed evolution of Cas9 nucleases. Genome Biol, 25(1):79, doi:10.1186/s13059-024-03215-9.
http://www.ncbi.nlm.nih.gov/pubmed/38528620
Michelatti D, Beyes S, Bernardis C, Negri ML, Morelli L, Bediaga NG, Poli V, Fagnocchi L, Lago S, D'Annunzio S, Cona N, Gaspardo I, Bianchi A, Jovetic J, Gianesello M, Turdo A, D'Accardo C, Gaggianesi M, Dori M, Forcato M, Crispatzu G, Rada-Iglesias A, Sosa MS, Timmers HTM, Bicciato S, Todaro M, Tiberi L, Zippo A (2024) Oncogenic enhancers prime quiescent metastatic cells to escape NK immune surveillance by eliciting transcriptional memory. Nat Commun, 15(1):2198, doi:10.1038/s41467-024-46524-0.
http://www.ncbi.nlm.nih.gov/pubmed/38503727
D'Ambrosio A, Bressan D, Ferracci E, Carbone F, Mulè P, Rossi F, Barbieri C, Sorrenti E, Fiaccadori G, Detone T, Vezzoli E, Bianchi S, Sartori C, Corso S, Fukuda A, Bertalot G, Falqui A, Barbareschi M, Romanel A, Pasini D, Chiacchiera F (2024) Increased genomic instability and reshaping of tissue microenvironment underlie oncogenic properties of Sci Adv, 10(11):eadh4435, doi:10.1126/sciadv.adh4435.
http://www.ncbi.nlm.nih.gov/pubmed/38489371
Zolfo M, Silverj A, Blanco-Míguez A, Manghi P, Rota-Stabelli O, Heidrich V, Jensen J, Maharjan S, Franzosa E, Menni C, Visconti A, Pinto F, Ciciani M, Huttenhower C, Cereseto A, Asnicar F, Kitano H, Yamada T, Segata N (2024) Discovering and exploring the hidden diversity of human gut viruses using highly enriched virome samples. bioRxiv, doi:10.1101/2024.02.19.580813.
http://www.ncbi.nlm.nih.gov/pubmed/38464031
Rotta G, Gilardoni E, Ravazza D, Mock J, Seehusen F, Elsayed A, Puca E, De Luca R, Pellegrino C, Look T, Weiss T, Manz MG, Halin C, Neri D, Dakhel Plaza S (2024) A novel strategy to generate immunocytokines with activity-on-demand using small molecule inhibitors. EMBO Mol Med, doi:10.1038/s44321-024-00034-0.
http://www.ncbi.nlm.nih.gov/pubmed/38448543
Tomasi F, Pozzi M, Lauria M (2024) Investigating the mechanisms underlying resistance to chemoterapy and to CRISPR-Cas9 in cancer cell lines. Sci Rep, 14(1):5402, doi:10.1038/s41598-024-55138-x.
http://www.ncbi.nlm.nih.gov/pubmed/38443409
Dalfovo D, Scandino R, Paoli M, Valentini S, Romanel A (2024) Germline determinants of aberrant signaling pathways in cancer. NPJ Precis Oncol, 8(1):57, doi:10.1038/s41698-024-00546-5.
http://www.ncbi.nlm.nih.gov/pubmed/38429380
Monaco S, Bussola N, Buttò S, Sona D, Giobergia F, Jurman G, Xinaris C, Apiletti D (2024) Author Correction: AI models for automated segmentation of engineered polycystic kidney tubules. Sci Rep, 14(1):4781, doi:10.1038/s41598-024-55389-8.
http://www.ncbi.nlm.nih.gov/pubmed/38413717
Mattavelli E, Piperni E, Asnicar F, Redaelli L, Grigore L, Pellegatta F, Nabinejad A, Tamburini S, Segata N, Catapano AL, Baragetti A (2024) High dietary inflammatory index associates with inflammatory proteins in plasma. Diabetol Metab Syndr, 16(1):50, doi:10.1186/s13098-024-01287-y.
http://www.ncbi.nlm.nih.gov/pubmed/38409061
Basso M, Gori A, Nardella C, Palviainen M, Holcar M, Sotiropoulos I, Bobis-Wozowicz S, D'Agostino VG, Casarotto E, Ciani Y, Suetsugu S, Gualerzi A, Martin-Jaular L, Boselli D, Kashkanova A, Parisse P, Lippens L, Pagliuca M, Blessing M, Frigerio R, Fourniols T, Meliciano A, Fietta A, Fioretti PV, Soroczyńska K, Picciolini S, Salviano-Silva A, Bergese P, Zocco D, Chiari M, Jenster G, Waldron L, Milosavljevic A, Nolan J, Monopoli MP, Witwer KW, Bussolati B, Di Vizio D, Falcon Perez J, Lenassi M, Cretich M, Demichelis F (2024) International Society for Extracellular Vesicles Workshop. QuantitatEVs: multiscale analyses, from bulk to single extracellular vesicle. J Extracell Biol, 3(1), doi:10.1002/jex2.137.
http://www.ncbi.nlm.nih.gov/pubmed/38405579
Alves Costa Silva C, Piccinno G, Suissa D, Bourgin M, Schreibelt G, Durand S, Birebent R, Fidelle M, Sow C, Aprahamian F, Manghi P, Punčochář M, Asnicar F, Pinto F, Armanini F, Terrisse S, Routy B, Drubay D, Eggermont AMM, Kroemer G, Segata N, Zitvogel L, Derosa L, Bol KF, de Vries IJM (2024) Influence of microbiota-associated metabolic reprogramming on clinical outcome in patients with melanoma from the randomized adjuvant dendritic cell-based MIND-DC trial. Nat Commun, 15(1):1633, doi:10.1038/s41467-024-45357-1.
http://www.ncbi.nlm.nih.gov/pubmed/38395948
Giuriato G, Romanelli MG, Bartolini D, Vernillo G, Pedrinolla A, Moro T, Franchi M, Locatelli E, Andani ME, Laginestra FG, Barbi C, Aloisi GF, Cavedon V, Milanese C, Orlandi E, De Simone T, Fochi S, Patuzzo C, Malerba G, Fabene P, Donadelli M, Stabile AM, Pistilli A, Rende M, Galli F, Schena F, Venturelli M (2024) Sex differences in neuromuscular and biological determinants of isometric maximal force. Acta Physiol (Oxf), doi:10.1111/apha.14118.
http://www.ncbi.nlm.nih.gov/pubmed/38385696
Masante L, Susin G, Baudet ML (2024) Droplet Digital PCR for the Detection and Quantification of Bona Fide CircRNAs. Methods Mol Biol, 2765:107-126, doi:10.1007/978-1-0716-3678-7_6.
http://www.ncbi.nlm.nih.gov/pubmed/38381336
Bazzani D, Heidrich V, Manghi P, Blanco-Miguez A, Asnicar F, Armanini F, Cavaliere S, Bertelle A, Dell'Acqua F, Dellasega E, Waldner R, Vicentini D, Bolzan M, Tomasi C, Segata N, Pasolli E, Ghensi P (2024) Favorable subgingival plaque microbiome shifts are associated with clinical treatment for peri-implant diseases. NPJ Biofilms Microbiomes, 10(1):12, doi:10.1038/s41522-024-00482-z.
http://www.ncbi.nlm.nih.gov/pubmed/38374114
Inno A, Veccia A, Madonia G, Berti A, Bortolotti R, Incorvaia L, Russo A, Caffo O, Gori S (2024) Risk of cardiovascular toxicity with combination of immune-checkpoint inhibitors and angiogenesis inhibitors: a meta-analysis. Front Cardiovasc Med, 11:1309100, doi:10.3389/fcvm.2024.1309100.
http://www.ncbi.nlm.nih.gov/pubmed/38370161
Huang KD, Amend L, Gálvez EJC, Lesker TR, de Oliveira R, Bielecka A, Blanco-Míguez A, Valles-Colomer M, Ruf I, Pasolli E, Buer J, Segata N, Esser S, Strowig T, Kehrmann J (2024) Establishment of a non-Westernized gut microbiota in men who have sex with men is associated with sexual practices. Cell Rep Med, 5(3):101426, doi:10.1016/j.xcrm.2024.101426.
http://www.ncbi.nlm.nih.gov/pubmed/38366600
Capasso M, Brignole C, Lasorsa VA, Bensa V, Cantalupo S, Sebastiani E, Quattrone A, Ciampi E, Avitabile M, Sementa AR, Mazzocco K, Cafferata B, Gaggero G, Vellone VG, Cilli M, Calarco E, Giusto E, Perri P, Aveic S, Fruci D, Tondo A, Luksch R, Mura R, Rabusin M, De Leonardis F, Cellini M, Coccia P, Iolascon A, Corrias MV, Conte M, Garaventa A, Amoroso L, Ponzoni M, Pastorino F (2024) From the identification of actionable molecular targets to the generation of faithful neuroblastoma patient-derived preclinical models. J Transl Med, 22(1):151, doi:10.1186/s12967-024-04954-w.
http://www.ncbi.nlm.nih.gov/pubmed/38351008
Lim WC, Marques Da Costa ME, Godefroy K, Jacquet E, Gragert L, Rondof W, Marchais A, Nhiri N, Dalfovo D, Viard M, Labaied N, Khan AM, Dessen P, Romanel A, Pasqualini C, Schleiermacher G, Carrington M, Zitvogel L, Scoazec JY, Geoerger B, Salmon J (2023) Divergent HLA variations and heterogeneous expression but recurrent HLA loss-of- heterozygosity and common Front Immunol, 14:1265469, doi:10.3389/fimmu.2023.1265469.
http://www.ncbi.nlm.nih.gov/pubmed/38318504
Alaimo A, Genovesi S, Annesi N, De Felice D, Subedi S, Macchia A, La Manna F, Ciani Y, Vannuccini F, Mugoni V, Notarangelo M, Libergoli M, Broso F, Taulli R, Ala U, Savino A, Cortese M, Mirzaaghaei S, Poli V, Bonapace IM, Papotti MG, Molinaro L, Doglioni C, Caffo O, Anesi A, Nagler M, Bertalot G, Carbone FG, Barbareschi M, Basso U, Dassi E, Pizzato M, Romanel A, Demichelis F, Kruithof-de Julio M, Lunardi A (2024) Sterile inflammation via TRPM8 RNA-dependent TLR3-NF-kB/IRF3 activation promotes antitumor immunity in prostate cancer. EMBO J, 43(5):780-805, doi:10.1038/s44318-024-00040-5.
http://www.ncbi.nlm.nih.gov/pubmed/38316991
Monaco S, Bussola N, Buttò S, Sona D, Giobergia F, Jurman G, Xinaris C, Apiletti D (2024) AI models for automated segmentation of engineered polycystic kidney tubules. Sci Rep, 14(1):2847, doi:10.1038/s41598-024-52677-1.
http://www.ncbi.nlm.nih.gov/pubmed/38310171
Reali F, Fochesato A, Kaddi C, Visintainer R, Watson S, Levi M, Dartois V, Azer K, Marchetti L (2023) A minimal PBPK model to accelerate preclinical development of drugs against tuberculosis. Front Pharmacol, 14:1272091, doi:10.3389/fphar.2023.1272091.
http://www.ncbi.nlm.nih.gov/pubmed/38239195
Manara V, Radoani M, Belli R, Peroni D, Destefanis F, Angheben L, Tome G, Tebaldi T, Bellosta P (2023) NOC1 is a direct MYC target, and its protein interactome dissects its activity in controlling nucleolar function. Front Cell Dev Biol, 11:1293420, doi:10.3389/fcell.2023.1293420.
http://www.ncbi.nlm.nih.gov/pubmed/38213308
Guerriero C, Manfredelli M, Matera C, Iuzzolino A, Conti L, Dallanoce C, De Amici M, Trisciuoglio D, Tata AM (2023) M2 Muscarinic Receptor Stimulation Induces Autophagy in Human Glioblastoma Cancer Stem Cells via mTOR Complex-1 Inhibition. Cancers (Basel), 16(1), doi:10.3390/cancers16010025.
http://www.ncbi.nlm.nih.gov/pubmed/38201453
Franceschini GM, Quaini O, Mizuno K, Orlando F, Ciani Y, Ku SY, Sigouros M, Rothmann E, Alonso A, Benelli M, Nardella C, Auh J, Freeman D, Hanratty B, Adil M, Elemento O, Tagawa ST, Feng FY, Caffo O, Buttigliero C, Basso U, Nelson PS, Corey E, Haffner MC, Attard G, Aparicio A, Demichelis F, Beltran H (2024) Noninvasive Detection of Neuroendocrine Prostate Cancer through Targeted Cell-free DNA Methylation. Cancer Discov, 14(3):424-445, doi:10.1158/2159-8290.CD-23-0754.
http://www.ncbi.nlm.nih.gov/pubmed/38197680
Cappelletto A, Alfì E, Volf N, Vu TVA, Bortolotti F, Ciucci G, Vodret S, Fantuz M, Perin M, Colliva A, Rozzi G, Rossi M, Ruozi G, Zentilin L, Vuerich R, Borin D, Lapasin R, Piazza S, Chiesa M, Lorizio D, Triboli L, Kumar S, Morello G, Tripodo C, Pinamonti M, Piperno GM, Benvenuti F, Rustighi A, Jo H, Piccolo S, Del Sal G, Carrer A, Giacca M, Zacchigna S (2024) EMID2 is a novel biotherapeutic for aggressive cancers identified by in vivo screening. J Exp Clin Cancer Res, 43(1):15, doi:10.1186/s13046-023-02942-4.
http://www.ncbi.nlm.nih.gov/pubmed/38195652
Vitali E, Grasso A, Schiavone ML, Trivellin G, Sobacchi C, Mione M, Mazziotti G, Lania A (2023) The direct impact of pegvisomant on osteoblast functions and bone development. J Endocrinol Invest, doi:10.1007/s40618-023-02281-3.
http://www.ncbi.nlm.nih.gov/pubmed/38159174
Bianconi I, Spath M, Aschbacher R, Pedron R, Wieser S, Pagani E (2024) Characterization of Verona Integron-Encoded Metallo-β-Lactamase-Type Carbapenemase-Producing Microb Drug Resist, 30(2):91-100, doi:10.1089/mdr.2023.0197.
http://www.ncbi.nlm.nih.gov/pubmed/38150043
Kratochvilová L, Vojsovič M, Valková N, Šislerová L, El Rashed Z, Inga A, Monti P, Brázda V (2023) The presence of a G-quadruplex prone sequence upstream of a minimal promoter increases transcriptional activity in the yeast Saccharomyces cerevisiae. Biosci Rep, 43(12), doi:10.1042/BSR20231348.
http://www.ncbi.nlm.nih.gov/pubmed/38112096
Valles-Colomer M, Manghi P, Cumbo F, Masetti G, Armanini F, Asnicar F, Blanco-Miguez A, Pinto F, Punčochář M, Garaventa A, Amoroso L, Ponzoni M, Corrias MV, Segata N (2024) Neuroblastoma is associated with alterations in gut microbiome composition subsequent to maternal microbial seeding. EBioMedicine, 99:104917, doi:10.1016/j.ebiom.2023.104917.
http://www.ncbi.nlm.nih.gov/pubmed/38104504
Rivosecchi J, Jurikova K, Cusanelli E (2024) Telomere-specific regulation of TERRA and its impact on telomere stability. Semin Cell Dev Biol, 157:3-23, doi:10.1016/j.semcdb.2023.11.001.
http://www.ncbi.nlm.nih.gov/pubmed/38088000
Fornasiero A, Fornoni S, Callovini A, Todesco B, Savoldelli A, Schena F, Holmberg HC, Pellegrini B, Bortolan L (2024) Analysis of Sprint Ski Mountaineering Performance. Int J Sports Physiol Perform, 19(2):155-163, doi:10.1123/ijspp.2023-0075.
http://www.ncbi.nlm.nih.gov/pubmed/38086366
Lago C, Federico A, Leva G, Mack NL, Schwalm B, Ballabio C, Gianesello M, Abballe L, Giovannoni I, Reddel S, Rossi S, Leone N, Carai A, Mastronuzzi A, Bisio A, Soldano A, Quintarelli C, Locatelli F, Kool M, Miele E, Tiberi L (2023) Patient- and xenograft-derived organoids recapitulate pediatric brain tumor features and patient treatments. EMBO Mol Med, 15(12):e18199, doi:10.15252/emmm.202318199.
http://www.ncbi.nlm.nih.gov/pubmed/38037472
Belkina AC, Roe CE, Tang VA, Back JB, Bispo C, Conway A, Chakraborty U, Daniels KT, de la Cruz G, Ferrer-Font L, Filby A, Gravano DM, Gregory MD, Hall C, Kukat C, Mozes A, Ordoñez-Rueda D, Orlowski-Oliver E, Pesce I, Porat Z, Poulton NJ, Reifel KM, Rieger AM, Sheridan RTC, Van Isterdael G, Walker RV (2024) Guidelines for establishing a cytometry laboratory. Cytometry A, 105(2):88-111, doi:10.1002/cyto.a.24807.
http://www.ncbi.nlm.nih.gov/pubmed/37941128
Florio F, Vencato S, Papa FT, Libergoli M, Kheir E, Ghzaiel I, Rando TA, Torrente Y, Biressi S (2023) Combinatorial activation of the WNT-dependent fibrogenic program by distinct complement subunits in dystrophic muscle. EMBO Mol Med, 15(12):e17405, doi:10.15252/emmm.202317405.
http://www.ncbi.nlm.nih.gov/pubmed/37927228
Burigotto M, Vigorito V, Gliech C, Mattivi A, Ghetti S, Bisio A, Lolli G, Holland AJ, Fava LL (2023) PLK1 promotes the mitotic surveillance pathway by controlling cytosolic 53BP1 availability. EMBO Rep, 24(12):e57234, doi:10.15252/embr.202357234.
http://www.ncbi.nlm.nih.gov/pubmed/37888778
Wang Z, Burigotto M, Ghetti S, Vaillant F, Tan T, Capaldo BD, Palmieri M, Hirokawa Y, Tai L, Simpson DS, Chang C, Huang AS, Lieschke E, Diepstraten ST, Kaloni D, Riffkin C, Huang DCS, Li Wai Suen CSN, Garnham AL, Gibbs P, Visvader JE, Sieber OM, Herold MJ, Fava LL, Kelly GL, Strasser A (2024) Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells. Cancer Discov, 14(2):362-379, doi:10.1158/2159-8290.CD-23-0402.
http://www.ncbi.nlm.nih.gov/pubmed/37877779
Vojsovič M, Kratochvilová L, Valková N, Šislerová L, El Rashed Z, Menichini P, Inga A, Monti P, Brázda V (2024) Transactivation by partial function P53 family mutants is increased by the presence of G-quadruplexes at a promoter site. Biochimie, 216:14-23, doi:10.1016/j.biochi.2023.09.026.
http://www.ncbi.nlm.nih.gov/pubmed/37838351
Bermingham KM, May A, Asnicar F, Capdevila J, Leeming ER, Franks PW, Valdes AM, Wolf J, Hadjigeorgiou G, Delahanty LM, Segata N, Spector TD, Berry SE (2024) Snack quality and snack timing are associated with cardiometabolic blood markers: the ZOE PREDICT study. Eur J Nutr, 63(1):121-133, doi:10.1007/s00394-023-03241-6.
http://www.ncbi.nlm.nih.gov/pubmed/37709944
Hellmich B, Sanchez-Alamo B, Schirmer JH, Berti A, Blockmans D, Cid MC, Holle JU, Hollinger N, Karadag O, Kronbichler A, Little MA, Luqmani RA, Mahr A, Merkel PA, Mohammad AJ, Monti S, Mukhtyar CB, Musial J, Price-Kuehne F, Segelmark M, Teng YKO, Terrier B, Tomasson G, Vaglio A, Vassilopoulos D, Verhoeven P, Jayne D (2024) EULAR recommendations for the management of ANCA-associated vasculitis: 2022 update. Ann Rheum Dis, 83(1):30-47, doi:10.1136/ard-2022-223764.
http://www.ncbi.nlm.nih.gov/pubmed/36927642