Latest publications of CIBIO affiliates (last updated on August 1st, 2017)

Massignan T, Sangiovanni V, Biggi S, Stincardini C, Elezgarai SR, Maietta G, Andreev IA, Ratmanova NK, Belov DS, Lukyanenko ER, Belov GM, Barreca ML, Altieri A, Kurkin AV, Biasini E (2017) A NOVEL SMALL MOLECULE INHIBITOR OF PRION REPLICATION AND MUTANT PRION PROTEIN TOXICITY. ChemMedChem, doi:10.1002/cmdc.201700302.
http://www.ncbi.nlm.nih.gov/pubmed/28722340

Carrion MDP, Marsicano S, Daniele F, Marte A, Pischedda F, Cairano ED, Piovesana E, von Zweydorf F, Kremmer E, Gloeckner CJ, Onofri F, Perego C, Piccoli G (2017) The LRRK2 G2385R variant is a partial loss-of-function mutation that affects synaptic vesicle trafficking through altered protein interactions. Sci Rep, 7(1):5377, doi:10.1038/s41598-017-05760-9.
http://www.ncbi.nlm.nih.gov/pubmed/28710481

Debora S, Yamila PL, Emiliano D, Martin M, Silvano P, Claudio S (2017) GTSE1: a novel TEAD4-E2F1 target gene involved in cell protrusions formation in triple-negative breast cancer cell models. Oncotarget, doi:10.18632/oncotarget.18691.
http://www.ncbi.nlm.nih.gov/pubmed/28700335

Debora S, Yamila PL, Emiliano D, Martin M, Silvano P, Claudio S (2017) Anti-SSTR2 peptide based targeted delivery of potent PLGA encapsulated 3,3´-diindolylmethane nanoparticles through blood brain barrier prevents glioma progression. Oncotarget, doi:10.18632/oncotarget.18689.
http://www.ncbi.nlm.nih.gov/pubmed/28700334

Pennuto M, Rinaldi C (2017) From gene to therapy in spinal and bulbar muscular atrophy: Are we there yet? Mol. Cell. Endocrinol., doi:10.1016/j.mce.2017.07.005.
http://www.ncbi.nlm.nih.gov/pubmed/28688959

Aronica E, Bauer S, Bozzi Y, Caleo M, Dingledine R, Gorter JA, Henshall DC, Kaufer D, Koh S, Löscher W, Louboutin JP, Mishto M, Norwood BA, Palma E, Poulter MO, Terrone G, Vezzani A, Kaminski RM (2017) Neuroinflammatory targets and treatments for epilepsy validated in experimental models. Epilepsia, 58 Suppl 3:27-38, doi:10.1111/epi.13783.
http://www.ncbi.nlm.nih.gov/pubmed/28675563

Romanel A, Garritano S, Stringa B, Blattner M, Dalfovo D, Chakravarty D, Soong D, Cotter KA, Petris G, Dhingra P, Gasperini P, Cereseto A, Elemento O, Sboner A, Khurana E, Inga A, Rubin MA, Demichelis F (2017) Inherited determinants of early recurrent somatic mutations in prostate cancer. Nat Commun, 8(1):48, doi:10.1038/s41467-017-00046-0.
http://www.ncbi.nlm.nih.gov/pubmed/28663546

Duranti S, Lugli GA, Mancabelli L, Armanini F, Turroni F, James K, Ferretti P, Gorfer V, Ferrario C, Milani C, Mangifesta M, Anzalone R, Zolfo M, Viappiani A, Pasolli E, Bariletti I, Canto R, Clementi R, Cologna M, Crifò T, Cusumano G, Fedi S, Gottardi S, Innamorati C, Masè C, Postai D, Savoi D, Soffiati M, Tateo S, Pedrotti A, Segata N, van Sinderen D, Ventura M (2017) Maternal inheritance of bifidobacterial communities and bifidophages in infants through vertical transmission. Microbiome, 5(1):66, doi:10.1186/s40168-017-0282-6.
http://www.ncbi.nlm.nih.gov/pubmed/28651630

Tett A, Pasolli E, Farina S, Truong DT, Asnicar F, Zolfo M, Beghini F, Armanini F, Jousson O, De Sanctis V, Bertorelli R, Girolomoni G, Cristofolini M, Segata N (2017) Unexplored diversity and strain-level structure of the skin microbiome associated with psoriasis. NPJ Biofilms Microbiomes, 3:14, doi:10.1038/s41522-017-0022-5.
http://www.ncbi.nlm.nih.gov/pubmed/28649415

Agostini S, Ali H, Vardabasso C, Fittipaldi A, Tasciotti E, Cereseto A, Bugatti A, Rusnati M, Lusic M, Giacca M (2017) Inhibition of Non Canonical HIV-1 Tat Secretion Through the Cellular Na(+),K(+)-ATPase Blocks HIV-1 Infection. EBioMedicine, 21:170-181, doi:10.1016/j.ebiom.2017.06.011.
http://www.ncbi.nlm.nih.gov/pubmed/28645727

Witt SH, Streit F, Jungkunz M, Frank J, Awasthi S, Reinbold CS, Treutlein J, Degenhardt F, Forstner AJ, Heilmann-Heimbach S, Dietl L, Schwarze CE, Schendel D, Strohmaier J, Abdellaoui A, Adolfsson R, Air TM, Akil H, Alda M, Alliey-Rodriguez N, Andreassen OA, Babadjanova G, Bass NJ, Bauer M, Baune BT, Bellivier F, Bergen S, Bethell A, Biernacka JM, Blackwood DHR, Boks MP, Boomsma DI, Børglum AD, Borrmann-Hassenbach M, Brennan P, Budde M, Buttenschøn HN, Byrne EM, Cervantes P, Clarke TK, Craddock N, Cruceanu C, Curtis D, Czerski PM, Dannlowski U, Davis T, de Geus EJC, Di Florio A, Djurovic S, Domenici E, Edenberg HJ, Etain B, Fischer SB, Forty L, Fraser C, Frye MA, Fullerton JM, Gade K, Gershon ES, Giegling I, Gordon SD, Gordon-Smith K, Grabe HJ, Green EK, Greenwood TA, Grigoroiu-Serbanescu M, Guzman-Parra J, Hall LS, Hamshere M, Hauser J, Hautzinger M, Heilbronner U, Herms S, Hitturlingappa S, Hoffmann P, Holmans P, Hottenga JJ, Jamain S, Jones I, Jones LA, Juréus A, Kahn RS, Kammerer-Ciernioch J, Kirov G, Kittel-Schneider S, Kloiber S, Knott SV, Kogevinas M, Landén M, Leber M, Leboyer M, Li QS, Lissowska J, Lucae S, Martin NG, Mayoral-Cleries F, McElroy SL, McIntosh AM, McKay JD, McQuillin A, Medland SE, Middeldorp CM, Milaneschi Y, Mitchell PB, Montgomery GW, Morken G, Mors O, Mühleisen TW, Müller-Myhsok B, Myers RM, Nievergelt CM, Nurnberger JI, O'Donovan MC, Loohuis LMO, Ophoff R, Oruc L, Owen MJ, Paciga SA, Penninx BWJH, Perry A, Pfennig A, Potash JB, Preisig M, Reif A, Rivas F, Rouleau GA, Schofield PR, Schulze TG, Schwarz M, Scott L, Sinnamon GCB, Stahl EA, Strauss J, Turecki G, Van der Auwera S, Vedder H, Vincent JB, Willemsen G, Witt CC, Wray NR, Xi HS, Bipolar Disorders Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Tadic A, Dahmen N, Schott BH, Cichon S, Nöthen MM, Ripke S, Mobascher A, Rujescu D, Lieb K, Roepke S, Schmahl C, Bohus M, Rietschel M (2017) Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia. Transl Psychiatry, 7(6):e1155, doi:10.1038/tp.2017.115.
http://www.ncbi.nlm.nih.gov/pubmed/28632202

Sanna MD, Quattrone A, Galeotti N (2017) Silencing of the RNA-binding protein HuR attenuates hyperalgesia and motor disability in experimental autoimmune encephalomyelitis. Neuropharmacology, 123:116-125, doi:10.1016/j.neuropharm.2017.06.005.
http://www.ncbi.nlm.nih.gov/pubmed/28599923

Rickman DS, Beltran H, Demichelis F, Rubin MA (2017) Biology and evolution of poorly differentiated neuroendocrine tumors. Nat. Med., 23(6):1-10, doi:10.1038/nm.4341.
http://www.ncbi.nlm.nih.gov/pubmed/28586335

Pistore C, Giannoni E, Colangelo T, Rizzo F, Magnani E, Muccillo L, Giurato G, Mancini M, Rizzo S, Riccardi M, Sahnane N, Del Vescovo V, Kishore K, Mandruzzato M, Macchi F, Pelizzola M, Denti MA, Furlan D, Weisz A, Colantuoni V, Chiarugi P, Bonapace IM (2017) DNA methylation variations are required for epithelial-to-mesenchymal transition induced by cancer-associated fibroblasts in prostate cancer cells. Oncogene, doi:10.1038/onc.2017.159.
http://www.ncbi.nlm.nih.gov/pubmed/28581528

Giesert F, Glasl L, Zimprich A, Ernst L, Piccoli G, Stautner C, Zerle J, Hölter SM, Vogt Weisenhorn DM, Wurst W (2017) The pathogenic LRRK2 R1441C mutation induces specific deficits modeling the prodromal phase of Parkinson's disease in the mouse. Neurobiol. Dis., 105:179-193, doi:10.1016/j.nbd.2017.05.013.
http://www.ncbi.nlm.nih.gov/pubmed/28576705

Lolli G, Naressi D, Sarno S, Battistutta R (2017) Characterization of the oligomeric states of the CK2 α2β2 holoenzyme in solution. Biochem. J., 474(14):2405-2416, doi:10.1042/BCJ20170189.
http://www.ncbi.nlm.nih.gov/pubmed/28572157

Domenici E (2017) Schizophrenia genetics comes to translation. NPJ Schizophr, 3:10, doi:10.1038/s41537-017-0011-y.
http://www.ncbi.nlm.nih.gov/pubmed/28560256

Petris G, Casini A, Montagna C, Lorenzin F, Prandi D, Romanel A, Zasso J, Conti L, Demichelis F, Cereseto A (2017) Hit and go CAS9 delivered through a lentiviral based self-limiting circuit. Nat Commun, 8:15334, doi:10.1038/ncomms15334.
http://www.ncbi.nlm.nih.gov/pubmed/28530235

Bassi S, Tripathi T, Monziani A, Di Leva F, Biagioli M (2017) Epigenetics of Huntington's Disease. Adv. Exp. Med. Biol., 978:277-299, doi:10.1007/978-3-319-53889-1_15.
http://www.ncbi.nlm.nih.gov/pubmed/28523552

Huang FW, Mosquera JM, Garofalo A, Oh C, Baco M, Amin-Mansour A, Rabasha B, Bahl S, Mullane SA, Robinson BD, Aldubayan S, Khani F, Karir B, Kim E, Chimene-Weiss J, Hofree M, Romanel A, Osborne JR, Kim JW, Azabdaftari G, Woloszynska-Read A, Sfanos K, De Marzo AM, Demichelis F, Gabriel S, Van Allen EM, Mesirov J, Tamayo P, Rubin MA, Powell IJ, Garraway LA (2017) Exome Sequencing of African-American Prostate Cancer Reveals Loss-of-Function ERF Mutations. Cancer Discov, doi:10.1158/2159-8290.CD-16-0960.
http://www.ncbi.nlm.nih.gov/pubmed/28515055

Jiménez Garduño AM, Juárez-Hernández LJ, Polanco MJ, Tosatto L, Michelatti D, Arosio D, Basso M, Pennuto M, Musio C (2017) Altered ionic currents and amelioration by IGF-1 and PACAP in motoneuron-derived cells modelling SBMA. Biophys. Chem., doi:10.1016/j.bpc.2017.05.003.
http://www.ncbi.nlm.nih.gov/pubmed/28511915

Fantappiè L, Irene C, De Santis M, Armini A, Gagliardi A, Tomasi M, Parri M, Cafardi V, Bonomi S, Ganfini L, Zerbini F, Zanella I, Carnemolla C, Bini L, Grandi A, Grandi G (2017) Some Gram-negative Lipoproteins Keep Their Surface Topology When Transplanted from One Species to Another and Deliver Foreign Polypeptides to the Bacterial Surface. Mol. Cell Proteomics, 16(7):1348-1364, doi:10.1074/mcp.M116.065094.
http://www.ncbi.nlm.nih.gov/pubmed/28483926

Roncador A, Jimenez-Garduño AM, Pasquardini L, Giusti G, Cornella N, Lunelli L, Potrich C, Bartali R, Aversa L, Verucchi R, Serra MD, Caponi S, Iannotta S, Macchi P, Musio C (2017) Primary cortical neurons on PMCS TiO2 films towards bio-hybrid memristive device: A morpho-functional study. Biophys. Chem., doi:10.1016/j.bpc.2017.04.010.
http://www.ncbi.nlm.nih.gov/pubmed/28476206

Conteduca V, Wetterskog D, Sharabiani MTA, Grande E, Fernandez-Perez MP, Jayaram A, Salvi S, Castellano D, Romanel A, Lolli C, Casadio V, Gurioli G, Amadori D, Font A, Vazquez-Estevez S, González Del Alba A, Mellado B, Fernandez-Calvo O, Méndez-Vidal MJ, Climent MA, Duran I, Gallardo E, Rodriguez A, Santander C, Sáez MI, Puente J, Gasi Tandefelt D, Wingate A, Dearnaley D, PREMIERE Collaborators, Spanish Oncology Genitourinary Group, Demichelis F, De Giorgi U, Gonzalez-Billalabeitia E, Attard G (2017) Androgen receptor gene status in plasma DNA associates with worse outcome on enzalutamide or abiraterone for castration-resistant prostate cancer: a multi-institution correlative biomarker study. Ann. Oncol., doi:10.1093/annonc/mdx155.
http://www.ncbi.nlm.nih.gov/pubmed/28472366

Prandi D, Baca SC, Romanel A, Barbieri CE, Mosquera JM, Fontugne J, Beltran H, Sboner A, Garraway LA, Rubin MA, Demichelis F (2017) Erratum to: Unraveling the clonal hierarchy of somatic genomic aberrations. Genome Biol., 18(1):80, doi:10.1186/s13059-017-1183-5.
http://www.ncbi.nlm.nih.gov/pubmed/28464947

Ieropoulos I, Pasternak G, Greenman J (2017) Urine disinfection and in situ pathogen killing using a Microbial Fuel Cell cascade system. PLoS ONE, 12(5):e0176475, doi:10.1371/journal.pone.0176475.
http://www.ncbi.nlm.nih.gov/pubmed/28463976

Querin G, Martinelli I, Bertolin C, Pegoraro E, Pennuto M, Sorarù G (2017) The role of AR polyQ tract in male breast carcinoma: lesson from an SBMA case. Ann. Oncol., 28(5):1160-1161, doi:10.1093/annonc/mdx038.
http://www.ncbi.nlm.nih.gov/pubmed/28453707

Paiardi C, Mirzoyan Z, Zola S, Parisi F, Vingiani A, Pasini ME, Bellosta P (2017) The Stearoyl-CoA Desaturase-1 (Desat1) in Drosophila cooperated with Myc to Induce Autophagy and Growth, a Potential New Link to Tumor Survival. Genes (Basel), 8(5), doi:10.3390/genes8050131.
http://www.ncbi.nlm.nih.gov/pubmed/28452935

Bozzi Y, Provenzano G, Casarosa S (2017) Neurobiological bases of autism-epilepsy comorbidity: a focus on excitation/inhibition imbalance. Eur. J. Neurosci., doi:10.1111/ejn.13595.
http://www.ncbi.nlm.nih.gov/pubmed/28452083

Zerbini F, Zanella I, Fraccascia D, König E, Irene C, Frattini LF, Tomasi M, Fantappiè L, Ganfini L, Caproni E, Parri M, Grandi A, Grandi G (2017) Large scale validation of an efficient CRISPR/Cas-based multi gene editing protocol in Escherichia coli. Microb. Cell Fact., 16(1):68, doi:10.1186/s12934-017-0681-1.
http://www.ncbi.nlm.nih.gov/pubmed/28438207

Ibarra MS, Borini Etichetti C, Di Benedetto C, Rosano GL, Margarit E, Del Sal G, Mione M, Girardini J (2017) Dynamic regulation of Pin1 expression and function during zebrafish development. PLoS ONE, 12(4):e0175939, doi:10.1371/journal.pone.0175939.
http://www.ncbi.nlm.nih.gov/pubmed/28426725

Rossi A, Moro A, Tebaldi T, Cornella N, Gasperini L, Lunelli L, Quattrone A, Viero G, Macchi P (2017) Identification and dynamic changes of RNAs isolated from RALY-containing ribonucleoprotein complexes. Nucleic Acids Res., doi:10.1093/nar/gkx235.
http://www.ncbi.nlm.nih.gov/pubmed/28379492

Romanel A, Zhang T, Elemento O, Demichelis F (2017) EthSEQ: ethnicity annotation from whole exome sequencing data. Bioinformatics, doi:10.1093/bioinformatics/btx165.
http://www.ncbi.nlm.nih.gov/pubmed/28369222

Sasi M, Vignoli B, Canossa M, Blum R (2017) Erratum to: Neurobiology of local and intercellular BDNF signaling. Pflugers Arch., 469(5-6):611, doi:10.1007/s00424-017-1971-5.
http://www.ncbi.nlm.nih.gov/pubmed/28361353